Evaluation of genetic kidney disease in living donor candidates

CP Thomas, J Divers - Living Kidney Donation: Best Practices in …, 2021 - Springer
Living donor transplantation is the preferred treatment for end-stage kidney disease (ESKD).
While living donor transplantation generally substantially enhances the quality of life and …

[HTML][HTML] Evaluation of genetic renal diseases in potential living kidney donors

S Kuppachi, RJH Smith, CP Thomas - Current transplantation reports, 2015 - Springer
Better outcomes for living donor transplantation, together with the shortened waiting time
and the increasing gap between supply and demand for kidneys for transplantation, has led …

[HTML][HTML] Evaluation of genetic kidney diseases in living donor kidney transplantation: towards precision genomic medicine in donor risk assessment

Y Caliskan, B Lee, AM Whelan, F Abualrub… - Current transplantation …, 2022 - Springer
Abstract Purpose of Review To provide a comprehensive update on the role of genetic
testing for the evaluation of kidney transplant recipient and living donor candidates. Recent …

Sequential genetic testing of living‐related donors for inherited renal disease to promote informed choice and enhance safety of living donation

CP Thomas, S Gupta, ME Freese… - Transplant …, 2021 - Wiley Online Library
Living kidney donors (LKDs) with a family history of renal disease are at risk of kidney
disease as compared to LKDs without such history suggesting that some LKDs may be pre …

[HTML][HTML] Is it time to utilize genetic testing for living kidney donor evaluation?

E Tantisattamo, UG Reddy, H Ichii, AJ Ferrey… - Nephron, 2022 - karger.com
Living donor kidney transplantation is an effective strategy to mitigate the challenges of solid
organ shortage. However, being a living kidney donor is not without risk, as donors may …

[HTML][HTML] Screening of living kidney donors for genetic diseases using a comprehensive genetic testing strategy

CP Thomas, MA Mansilla, R Sompallae… - American journal of …, 2017 - Elsevier
Related living kidney donors (LKDs) are at higher risk of end-stage renal disease (ESRD)
compared with unrelated LKDs. A genetic panel was developed to screen 115 genes …

Screening of Living Kidney Donors for Genetic Diseases: Commentary

RW Steiner - Kidney360, 2024 - journals.lww.com
A genetic basis has been suggested for increased ESKD risks in living kidney donors who
are closely related to their recipients, in Black living donors compared to nonblacks, and in …

[HTML][HTML] Genetic evaluation of living kidney donor candidates: A review and recommendations for best practices

CP Thomas, R Daloul, KL Lentine, R Gohh… - American journal of …, 2023 - Elsevier
The growing accessibility and falling costs of genetic sequencing techniques has expanded
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …

Evaluation of Indications for Genetic Assessment in Living Kidney Transplant Donors and Relevant Canadian Practices in Light of the Current International Guidelines …

S Zahran, KF Bei, A Adil, PN Okoh… - Journal of the American …, 2023 - journals.lww.com
Background: End stage renal disease (ESRD) is a prevalent condition with tendency for
familial clustering. Living kidney donor transplantation is a superior treatment option …

Risk of kidney disease after living kidney donation

AJ Matas, AD Rule - Nature Reviews Nephrology, 2021 - nature.com
Living donor kidney transplantation benefits the recipient. However, kidney failure can occur
in a small fraction of donors—the risk is not uniform but varies according to donor …