[PDF][PDF] Ketamine: Mechanisms, Applications, and Future Directions

I Karunarathna, K Kusumarathna… - Uva Clinical Lab …, 2024 - researchgate.net
Ketamine, a versatile anesthetic agent with a complex pharmacological profile, has been
utilized in clinical practice for decades3. This review examines the diverse mechanisms of …

[HTML][HTML] Ketamine use in current clinical practice

M Gao, D Rejaei, H Liu - Acta Pharmacologica Sinica, 2016 - nature.com
After nearly half a century on the market, ketamine still occupies a unique corner in the
medical armamentarium of anesthesiologists or clinicians treating pain. Over the last two …

Ketamine—a narrative review of its uses in medicine

BM Radvansky, S Puri, AN Sifonios… - American Journal of …, 2016 - journals.lww.com
One of the most fascinating drugs in the anesthesiologist's armament is ketamine, an N-
methyl-D-aspartate receptor antagonist with a myriad of uses. The drug is a dissociative …

A review of nonanesthetic uses of ketamine

A Pribish, N Wood, A Kalava - Anesthesiology research and …, 2020 - Wiley Online Library
Ketamine, a nonselective NMDA receptor antagonist, is used widely in medicine as an
anesthetic agent. However, ketamine's mechanisms of action lead to widespread …

[HTML][HTML] Ketamine

SB Rosenbaum, V Gupta, P Patel, JL Palacios - 2017 - europepmc.org
Ketamine - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC
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An update on the basic and clinical science of ketamine analgesia

LV Doan, J Wang - The Clinical journal of pain, 2018 - journals.lww.com
Objective: In the context of the current opioid epidemic, there has been a renewed interest in
the use of ketamine as an analgesic agent. Methods: We reviewed ketamine analgesia …

Ketamine: an update on cellular and subcellular mechanisms with implications for clinical practice

GJ Iacobucci, O Visnjevac, L Pourafkari… - Pain …, 2017 - search.proquest.com
BACKGROUND: Ketamine is one of the oldest hypnotic agents used to provide an
anesthetic agent with analgesic properties and minimal suppressive effects on respiration …

Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms

P Zanos, R Moaddel, PJ Morris, LM Riggs… - Pharmacological …, 2018 - ASPET
Ketamine, a racemic mixture consisting of (S)-and (R)-ketamine, has been in clinical use
since 1970. Although best characterized for its dissociative anesthetic properties, ketamine …

[HTML][HTML] Ketamine, an old–new drug: uses and abuses

K Savić Vujović, A Jotić, B Medić, D Srebro, A Vujović… - Pharmaceuticals, 2023 - mdpi.com
Ketamine as an old–new drug has a variety of clinical implications. In the last 30 years,
ketamine has become popular for acute use in humans. Ketamine in standard doses is …

Ketamine‐an update on its clinical uses and abuses

J Xu, H Lei - CNS neuroscience & therapeutics, 2014 - Wiley Online Library
This review highlights the recent clinical research that supports the therapeutic utility of
ketamine as a multifaceted drug. After long‐term use as a dissociative anesthetic, it has re …