The overarching objective is to review how early exposure to adversity interacts with
inflammation to alter brain maturation. Both adversity and inflammation are significant risk …

Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

The role of the innate immune system in mediating some of the consequences of childhood
abuse and neglect has received increasing attention in recent years. Most of the work to …

Early exposure to psychosocial adversity is among the most potent predictors of depression.
Because depression commonly emerges prior to adulthood, we must consider the …

It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …

A review of the human developmental neuroimaging literature that investigates outcomes
following exposure to psychosocial adversity is presented with a focus on two subcortical …

Adversity in early childhood exerts an enduring impact on mental and physical health,
academic achievement, lifetime productivity, and the probability of interfacing with the …

Children exposed to various forms of adversity early in life are at increased risk for a broad
range of developmental difficulties, affecting both cognitive and emotional adjustment. We …

Adversity early in life is common and is a major risk factor for the onset of psychopathology.
Delineating the neurodevelopmental pathways by which early adversity affects mental …