Role of coagulation in persistent renal ischemia following reperfusion in an animal model
JH Dominguez, D Xie… - American Journal of …, 2022 - journals.physiology.org
Ischemic acute kidney injury is common, deadly, and accelerates the progression of chronic
kidney disease, yet has no specific therapy. After ischemia, reperfusion is patchy with early …
kidney disease, yet has no specific therapy. After ischemia, reperfusion is patchy with early …
Acute renal failure after whole body ischemia is characterized by inflammation and T cell-mediated injury
MJ Burne-Taney, J Kofler, N Yokota… - … of physiology-renal …, 2003 - journals.physiology.org
Acute renal failure (ARF) commonly occurs after whole body ischemia. Most experimental
models of ARF have relied on the isolated renal artery clamping model; however, there is a …
models of ARF have relied on the isolated renal artery clamping model; however, there is a …
Ischemia-reperfusion injury of rat kidney relates more to tubular than to microcirculatory disturbances
M Yin, HAJM Kurvers, GJ Tangelder, MH Booster… - Renal failure, 1996 - Taylor & Francis
Several pathophysiological mechanisms have been purported to be involved in the
development of acute ischemic renal failure, such as impairment of tubular function and/or of …
development of acute ischemic renal failure, such as impairment of tubular function and/or of …
Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury
M Horbelt, SY Lee, HE Mang… - American Journal …, 2007 - journals.physiology.org
Functional and structural abnormalities in the renal microvasculature are important
processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). In this …
processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). In this …
Repetitive brief ischemia: intermittent reperfusion during ischemia ameliorates the extent of injury in the perfused kidney
DA Willgoss, B Zhang, GC Gobé, M Kadkhodaee… - Renal failure, 2003 - Taylor & Francis
Acute renal failure commonly follows reduced renal perfusion or ischemia. Reperfusion is
essential for recovery but can itself cause functional and structural injury to the kidney. The …
essential for recovery but can itself cause functional and structural injury to the kidney. The …
Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury
O Kwon, SM Hong, TA Sutton… - American Journal of …, 2008 - journals.physiology.org
Decreased renal blood flow following an ischemic insult contributes to a reduction in
glomerular filtration. However, little is known about the underlying cellular or subcellular …
glomerular filtration. However, little is known about the underlying cellular or subcellular …
Chronic reduction in renal mass in the rat attenuates ischemia/reperfusion injury and does not impair tubular regeneration
SR VERCAUTEREN, DK YSEBAERT… - Journal of the …, 1999 - journals.lww.com
It is not known whether a kidney with chronic structural and functional changes is more
vulnerable to an acute renal insult, and whether its regeneration capacity after injury is …
vulnerable to an acute renal insult, and whether its regeneration capacity after injury is …
The microcirculation of the septic kidney
L Zafrani, D Payen, E Azoulay, C Ince - Seminars in nephrology, 2015 - Elsevier
The renal microcirculation plays a major role in the delivery of blood and oxygen to the
kidney. In sepsis, alterations in renal microvascular perfusion, in conjunction with increased …
kidney. In sepsis, alterations in renal microvascular perfusion, in conjunction with increased …
Murine renal ischaemia‐reperfusion injury (Methods in Renal Research Paper)
SE Kennedy, JH Erlich - Nephrology, 2008 - Wiley Online Library
Ischaemia/reperfusion is a major cause of acute kidney injury in native and transplant
kidneys and is associated with significant morbidity and mortality. Murine models of renal …
kidneys and is associated with significant morbidity and mortality. Murine models of renal …
Mediators of ischemic renal injury
JV Bonventre - Annual review of medicine, 1988 - annualreviews.org
Acute renal failure is a serious consequence of renal ischemia. The diagnosis carries an
associated high mortality rate. When blood flow to the kidneys is inadequate to supply …
associated high mortality rate. When blood flow to the kidneys is inadequate to supply …