Uncontrolled exsanguination remains the leading cause of death for trauma patients, many
of whom die in the pre-hospital setting. Without expedient intervention, trauma-associated …

Achieving hemostasis is a crucial focus of clinicians working in surgical and trauma settings.
Topical hemostatic agents—including mechanical hemostats, active hemostats, flowable …

Results: Hemostatic agents can establish hemostasis by means of different mechanisms,
including concentrating coagulation factors, adhesion to the tissues, in which traumatic …

Background A wide variety of hemostats are available as adjunctive measures to improve
hemostasis during surgical procedures if residual bleeding persists despite correct …

Since ancient times we have attempted to facilitate hemostasis by application of topical
agents. In the last decade, the number of different effective hemostatic agents has increased …

A wide variety of topical hemostats are approved as adjunctive therapies in the maintenance
of hemostasis during surgical procedures in which conventional methods are insufficient or …

A number of new hemostatic products have been developed recently for use in trauma
settings of severe uncontrolled bleeding. Currently, the literature on these products is …

Severe hemorrhage causes significant metabolic and cellular dysfunction secondary to
deficient tissue perfusion and oxygen delivery. If bleeding continues, hemodynamic …

Hemorrhage is the leading cause of preventable death in combat trauma and the secondary
cause of death in civilian trauma. A significant number of deaths due to hemorrhage occur …

BACKGROUND: Uncontrolled haemorrhage is a leading cause of prehospital death after
military and civilian trauma. Exsanguination from extremity wounds causes over half of …