The complement cascade comprises soluble and cell surface proteins and is an important
arm of the innate immune system. Once activated, the complement system rapidly generates …

The complement cascade was first recognized as a downstream effector system of antibody-
mediated cytotoxicity. Consistent with this view, it was discovered in the 1960s that …

Although the complement system is primarily perceived as a host defence system, a more
versatile, yet potentially more harmful side of this innate immune pathway as an …

The complement system is involved in several aspects of renal disease, including primary
renal diseases, dialysis and renal transplant rejection. Initially, a role for complement in …

Complement is an important component of the innate immune system that is crucial for
defense from microbial infections and for clearance of immune complexes and injured cells …

The complement cascade is part of the innate immune system whose actions protect hosts
from pathogens. Recent research shows complement involvement in a wide spectrum of …

The complement cascade, traditionally considered an effector arm of innate immunity
required for host defense against pathogens, is now recognized as a crucial pathogenic …

Complement is a part of the body's innate immune system that helps defend the host from
microbial infection. It is tightly controlled by a number of cell surface and fluid‐phase …

The complement activation system plays important roles to maintain homeostasis in the host
and to fight foreign invaders to protect the host. Therefore, the complement system is …

The complement cascade is a vital component of both the innate and adaptive immune
systems. Complement activation also contributes to the pathogenesis of many diseases …