A CRISPR/Cas9 based polymeric nanoparticles to treat/inhibit microbial infections
The latest breakthrough towards the adequate and decisive methods of gene editing tools
provided by CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic …
provided by CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic …
Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy
Genome editing using the clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR associated 9 (Cas9) technology is revolutionizing the study of gene …
(CRISPR)/CRISPR associated 9 (Cas9) technology is revolutionizing the study of gene …
Biomaterial-assisted targeted and controlled delivery of CRISPR/Cas9 for precise gene editing
RISPR-Cas9 has exhibited enormous potential in gene therapy. It can perform genome
editing with single-nucleotide precision in various types of cell and tissue, providing a …
editing with single-nucleotide precision in various types of cell and tissue, providing a …
[HTML][HTML] Applications and research advances in the delivery of CRISPR/Cas9 systems for the treatment of inherited diseases
X Lu, M Zhang, G Li, S Zhang, J Zhang, X Fu… - International journal of …, 2023 - mdpi.com
The rapid advancements in gene therapy have opened up new possibilities for treating
genetic disorders, including Duchenne muscular dystrophy, thalassemia, cystic fibrosis …
genetic disorders, including Duchenne muscular dystrophy, thalassemia, cystic fibrosis …
[HTML][HTML] Lipid nanoparticle-mediated efficient delivery of CRISPR/Cas9 for tumor therapy
The emerging CRISPR/Cas9 system represents a promising platform for genome editing.
However, its low transfection efficiency is a major problem hampering the application of the …
However, its low transfection efficiency is a major problem hampering the application of the …
Delivering CRISPR: a review of the challenges and approaches
CA Lino, JC Harper, JP Carney, JA Timlin - Drug delivery, 2018 - Taylor & Francis
Gene therapy has long held promise to correct a variety of human diseases and defects.
Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the …
Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the …
CRISPR-Cas9 for cancer therapy: Opportunities and challenges
Cancer is a genetic disease stemming from cumulative genetic/epigenetic aberrations.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9-mediated …
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9-mediated …
[HTML][HTML] Efficient viral delivery of Cas9 into human safe harbor
H Hayashi, Y Kubo, M Izumida, T Matsuyama - Scientific Reports, 2020 - nature.com
Gene editing using CRISPR/Cas9 is a promising method to cure many human genetic
diseases. We have developed an efficient system to deliver Cas9 into the adeno-associated …
diseases. We have developed an efficient system to deliver Cas9 into the adeno-associated …
[HTML][HTML] Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …
[HTML][HTML] Integrase-deficient lentiviral vector as an all-in-one platform for highly efficient CRISPR/Cas9-mediated gene editing
PI Ortinski, B O'Donovan, X Dong, B Kantor - Molecular therapy Methods & …, 2017 - cell.com
The CRISPR/Cas9 systems have revolutionized the field of genome editing by providing
unprecedented control over gene sequences and gene expression in many species …
unprecedented control over gene sequences and gene expression in many species …