[HTML][HTML] Recent Advances in CRISPR/Cas9 Delivery Approaches for Therapeutic Gene Editing of Stem Cells
M Lotfi, D Morshedi Rad, SS Mashhadi… - Stem cell reviews and …, 2023 - Springer
Rapid advancement in genome editing technologies has provided new promises for treating
neoplasia, cardiovascular, neurodegenerative, and monogenic disorders. Recently, the …
neoplasia, cardiovascular, neurodegenerative, and monogenic disorders. Recently, the …
A dual-targeting delivery system for effective genome editing and in situ detecting related protein expression in edited cells
BY Liu, XY He, C Xu, L Xu, SL Ai, SX Cheng… - …, 2018 - ACS Publications
One of critical steps in genome editing by CRISPR-Cas9 is to deliver the CRISPR-Cas9
system into targeted cells. In this study, we developed a dual-targeting delivery system …
system into targeted cells. In this study, we developed a dual-targeting delivery system …
Mechanism and applications of CRISPR/Cas-9-mediated genome editing
M Asmamaw, B Zawdie - Biologics: targets and therapy, 2021 - Taylor & Francis
Clustered regularly interspaced short palindromic repeat (CRISPR) and their associated
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
protein (Cas-9) is the most effective, efficient, and accurate method of genome editing tool in …
CRISPR-Cas systems for editing, regulating and targeting genomes
JD Sander, JK Joung - Nature biotechnology, 2014 - nature.com
Targeted genome editing using engineered nucleases has rapidly gone from being a niche
technology to a mainstream method used by many biological researchers. This widespread …
technology to a mainstream method used by many biological researchers. This widespread …
Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
S Deng, X Li, S Liu, J Chen, M Li, SY Chew… - Science …, 2020 - science.org
Controlled release of CRISPR-Cas9 ribonucleoprotein (RNP) and codelivery with other
drugs remain a challenge. We demonstrate controlled release of CRISPR-Cas9 RNP and …
drugs remain a challenge. We demonstrate controlled release of CRISPR-Cas9 RNP and …
CRISPR/Cas9 for genome editing: progress, implications and challenges
F Zhang, Y Wen, X Guo - Human molecular genetics, 2014 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
(Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling …
(Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling …
Split Cas9, not hairs− advancing the therapeutic index of CRISPR technology
C Schmelas, D Grimm - Biotechnology Journal, 2018 - Wiley Online Library
The discovery that the bacterial CRISPR/Cas9 system can be translated into mammalian
cells continues to have an unprecedented impact on the biomedical research community, as …
cells continues to have an unprecedented impact on the biomedical research community, as …
CRISPR/Cas gene therapy
B Zhang - Journal of cellular physiology, 2021 - Wiley Online Library
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated
enzyme (Cas) is a naturally occurring genome editing tool adopted from the prokaryotic …
enzyme (Cas) is a naturally occurring genome editing tool adopted from the prokaryotic …
CRISPR/Cas system: a game changing genome editing technology, to treat human genetic diseases
Genes, are the functional units of heredity that used as an instructors to make proteins either
to become the functional or structural part of the cell. Hence, the proteins get more attention …
to become the functional or structural part of the cell. Hence, the proteins get more attention …
Adenoviral vectors for in vivo delivery of CRISPR-Cas gene editors
Harnessing the bacterial clustered regularly interspaced short palindromic repeats
(CRISPR) system for genome editing in eukaryotes has revolutionized basic biomedical …
(CRISPR) system for genome editing in eukaryotes has revolutionized basic biomedical …