Host cell interactions and signalling with Neisseria gonorrhoeae

M Naumann, T Rudel, TF Meyer - Current opinion in microbiology, 1999 - Elsevier
Neisseria gonorrhoeae is a highly adapted human pathogen that utilises multiple adhesins
to interact with a variety of host cell receptors. Recently, substantial progress has been made …

Implications of molecular contacts and signaling initiated by Neisseria gonorrhoeae

M Koomey - Current opinion in microbiology, 2001 - Elsevier
Neisseria gonorrhoeae employs diverse strategies with which to adhere to and invade host
cells during the course of infection. These primary encounters provide means by which …

[HTML][HTML] Mechanisms of host manipulation by Neisseria gonorrhoeae

E Walker, S van Niekerk, K Hanning, W Kelton… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages

A Château, HS Seifert - Cellular microbiology, 2016 - Wiley Online Library
The human‐adapted organism Neisseria gonorrhoeae is the causative agent of gonorrhoea,
a sexually transmitted infection. It readily colonizes the genital, rectal and nasalpharyngeal …

Neisseria gonorrhoeae Infection Protects Human Endocervical Epithelial Cells from Apoptosis via Expression of Host Antiapoptotic Proteins

SA Follows, J Murlidharan, P Massari… - Infection and …, 2009 - Am Soc Microbiol
Several microbial pathogens can modulate the host apoptotic response to infection, which
may contribute to immune evasion. Various studies have reported that infection with the …

Neisseria gonorrhoeae physiology and pathogenesis

LR Green, J Cole, EFD Parga, JG Shaw - Advances in microbial physiology, 2022 - Elsevier
Neisseria gonorrhoeae is an obligate human pathogen that is the cause of the sexually
transmitted disease gonorrhoea. Recently, there has been a surge in gonorrhoea cases that …

Gonococcal defenses against antimicrobial activities of neutrophils

A Palmer, AK Criss - Trends in microbiology, 2018 - cell.com
Neisseria gonorrhoeae initiates a strong local immune response that is characterized by
copious recruitment of neutrophils to the site of infection. Neutrophils neutralize microbes by …

Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes

A Chen, HS Seifert - Infection and immunity, 2011 - Am Soc Microbiol
The human pathogen Neisseria gonorrhoeae recruits and interacts extensively with
polymorphonuclear leukocytes (PMNs) during infection. N. gonorrhoeae is able to survive …

Distinct Proinflammatory Host Responses to Neisseria gonorrhoeae Infection in Immortalized Human Cervical and Vaginal Epithelial Cells

RN Fichorova, PJ Desai, FC Gibson III… - Infection and …, 2001 - Am Soc Microbiol
In this study we utilized immortalized morphologically and functionally distinct epithelial cell
lines from normal human endocervix, ectocervix, and vagina to characterize gonococcal …

[HTML][HTML] Neisseria gonorrhoeae Suppresses Dendritic Cell-Induced, Antigen-Dependent CD4 T Cell Proliferation

W Zhu, MS Ventevogel, KJ Knilans, JE Anderson… - PloS one, 2012 - journals.plos.org
Neisseria gonorrhoeae is the second most common sexually transmitted bacterial pathogen
worldwide. Diseases associated with N. gonorrhoeae cause localized inflammation of the …