The limited availability of deceased human organs and cells for the purposes of clinical
transplantation remains critical worldwide. Despite the increasing utilization of 'high …

Between the 17th and 20th centuries, blood was transfused from various animal species into
patients with a variety of pathological conditions. Skin grafts were carried out in the 19th …

The shortage of donated human organs for transplantation continues to be a life threatening
problem for patients suffering from complete organ failure. Although this gap is increasing …

The ability to use animal organs, such as from the pig, for the purposes of transplantation in
humans, would clearly overcome the major shortage of human organs that greatly restricts …

The shortage of donor organs is a major barrier to clinical organ transplantation. Although
xenotransplantation is considered one of the alternatives to human organ transplantation …

▪ Abstract The increasing shortage of human cadaveric organs for purposes of
transplantation has become the critical limiting factor in the number of transplants performed …

Binding of natural anti-pig antibodies in humans and nonhuman primates to carbohydrate
antigens expressed on the transplanted pig organ, the most important of which is galactose …

Miniature swine have several advantages over other potential donor species as a xenograft
donor for clinical use. Among these advantages are: 1) unlimited availability; 2) size (similar …

If the immunological problems could be overcome, the ideal animal organ donor for man
would be an animal that is readily available throughout the world in large numbers and …

The availability of cells, tissues and organs from a non‐human species such as the pig
could, at least in theory, meet the demand of organs necessary for clinical transplantation. At …