Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature

G Caramori, P Ruggeri, F Arpinelli, L Salvi… - International journal of …, 2019 - Taylor & Francis
Patients with chronic obstructive pulmonary disease (COPD) demonstrate a greater
osteoporosis prevalence than the general population. This osteoporosis risk may be …

Inhaled corticosteroids can reduce osteoporosis in female patients with COPD

SF Liu, HC Kuo, GH Liu, SC Ho, HC Chang… - … journal of chronic …, 2016 - Taylor & Francis
Background Whether the use of inhaled corticosteroids (ICSs) in patients with COPD can
protect from osteoporosis remains undetermined. The aim of this study is to assess the …

Evaluating the association of osteoporosis with inhaled corticosteroid use in chronic obstructive pulmonary disease in Taiwan

KL Chiu, CC Lee, CY Chen - Scientific Reports, 2021 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation and
osteoporosis is the major comorbidity associated with poor prognosis in COPD. However …

Long-term therapy in COPD: any evidence of adverse effect on bone?

A Langhammer, S Forsmo… - International journal of …, 2009 - Taylor & Francis
Patients with COPD have high risk for osteoporosis and fractures. Hip and vertebral fractures
might impair mobility, and vertebral fractures further reduce lung function. This review …

Inhaled corticosteroids and fractures in chronic obstructive pulmonary disease: current understanding and recommendations

JY Moon, DD Sin - Current opinion in pulmonary medicine, 2019 - journals.lww.com
ICS increases risk of bone demineralization and fracture in patients with COPD. It should be
generally avoided in patients with previous fractures or significant osteoporosis. If they are …

Use of high-dose intermittent systemic glucocorticoids and the risk of fracture in patients with chronic obstructive pulmonary disease

OA Oshagbemi, AM Burden, KN Shudofsky… - Bone, 2018 - Elsevier
Introduction Chronic obstructive pulmonary disease (COPD) is characterised by persistent
airflow obstruction and respiratory symptoms. While short course systemic GCs are …

Fracture risk associated with inhaled corticosteroid use in chronic obstructive pulmonary disease

TA Lee, KB Weiss - American journal of respiratory and critical care …, 2004 - atsjournals.org
Patients with chronic obstructive pulmonary disease (COPD) are frequently treated with
inhaled corticosteroids (ICS). However, the impact of ICS use on fracture risk remains …

Risk of Fracture and Osteoporosis in Patients With COPD and Inhaled Corticosteroids Treatment

N Zhang, X Fan, Y Zhang, N Xu, L Li - Respiratory Care, 2023 - rc.rcjournal.com
BACKGROUND: There are disputes whether inhaled corticosteroids (ICS) increase the
incidence of fracture or osteoporosis among patients with COPD. The aim of this meta …

Effect of fracture risk in inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis

S Peng, C Tan, L Du, Y Niu, X Liu, R Wang - BMC Pulmonary Medicine, 2023 - Springer
Background The fracture risk of patients with chronic obstructive pulmonary disease (COPD)
treated with inhaled corticosteroids is controversial. And some large-scale randomized …

Do inhaled steroids reduce bone mineral density and increase fracture risk?

C Wheelock, J Glass, L St Anna - 2012 - mospace.umsystem.edu
Inhaled corticosteroids (ICS) at low to medium doses (< 1500 mcg beclomethasone
hydrofluoroalkane per day) for asthma and chronic obstructive pulmonary disease (COPD) …