Valvular heart disease affects about 2.5% of the United States population and its incidence
is projected to increase as a result of the increasing global prevalence of cardiometabolic …

Objective Ideal heart valve solutions aim to provide thrombosis-free durability. A scaffold-
based polycarbonate urethane urea tissue-engineered heart valve designed to mimic native …

A novel tissue-engineered heart valve (TEHV) was fabricated from a decellularized tissue
tube mounted on a frame with three struts, which upon back-pressure cause the tube to …

Background and purpose of the study The use of decellularised biological heart valves in
the replacement of damaged heart valves offers a promising solution to reduce the …

Background: The best storage preservation method for maintaining the quality and safety of
human decellularized allograft heart valves is yet to be established. Objective: The aim of …

The production of viable biological heart valves is of central interest in tissue engineering
(TE). The aim of this study was to generate decellularized heart valves with an intact ultra …

Tissue-engineered heart valves (TEHV) have been proposed as a promising solution for the
clinical needs of pediatric patients. In vivo studies have shown TEHV leaflet contraction and …

Well documented shortcomings of current heart valve substitutes–biological and mechanical
prostheses make them imperfect choices for patients diagnosed with heart valve disease, in …

OBJECTIVES Decellularization is an alternative method for processing biological tissues
with decreased antigenicity and resistance to calcification. The aim of this study was to …