Psoriasis, an immune-mediated inflammatory disease, is associated with poor pregnancy
outcomes. Emerging evidence indicates that these defects are likely attributed to …

Maternal diabetes has been widely reported to adversely affect oocyte quality. Although
various molecules and pathways may be involved in this process, strategies to prevent …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Levels of cotinine, a major metabolite of nicotine, have been positively correlated with risks
of cigarette smoking-related diseases. Melatonin is synthesized by the pineal gland and has …

Chronic stress which is common in the current society can be harmful to female reproduction
and is associated with oocyte defects. However, the underlying mechanisms remain largely …

Background Melatonin, as a free radical scavenger exhibiting genomic actions, regulates
the antioxidant genes expression and apoptosis mechanisms. In polycystic ovary syndrome …

Deoxynivalenol (DON) is one of the most prevalent fusarium mycotoxins in feedstuff and
food. DON causes detrimental effects on human and animal reproductive systems by …

Age-related decline in female fertility is a common feature that occurs in the fourth decade of
women as a result of a reduction in both oocyte quality and quantity [1]. However, strategies …

With increase in women's age, the reproductive capability of female mammals decreases
dramatically caused by age-related oxidative stress, coinciding with the decline in the …

Oxybenzone (OBZ), an ultraviolet light filter that is widely used in sunscreens and cosmetics,
is an emerging contaminant found in humans and the environment. Recent studies have …