Asthma and asthma-related traits are complex diseases with strong genetic and
environmental components. Rapid progress in asthma genetics has led to the identification …

Asthma, atopy, and related phenotypes are heterogeneous complex traits, with both genetic
and environmental risk factors. Extensive research has been conducted and over hundred …

Asthma, an inflammatory disorder of the airways, is the most common chronic disease of
children worldwide. There are significant racial/ethnic disparities in asthma prevalence …

Background Genome‐wide association studies (GWAS s) have identified various genes
associated with asthma, yet, causal genes or single nucleotide polymorphisms (SNP s) …

Even though heritability estimates suggest that the risk of asthma, hay fever and eczema is
largely due to genetic factors, previous studies have not explained a large part of the …

An increasing proportion of the worldwide population is affected by allergic diseases such
as allergic rhinitis (AR), atopic dermatitis (AD) and allergic asthma and improved treatment …

Asthma exacerbations are among the most frequent causes of hospitalization during
childhood, but the underlying mechanisms are poorly understood. We performed a genome …

Background Childhood asthma is strongly influenced by genetics and is a risk factor for
reduced lung function and chronic obstructive pulmonary disease (COPD) in adults. This …

Genome-wide association studies followed by replication provide a powerful approach to
map genetic risk factors for asthma. We sought to search for new variants associated with …

Chromosome 17q21 contains a cluster of genes including ORMDL3 and GSDMB, which
have been highly linked to asthma in genome-wide association studies. ORMDL3 is …