A sequence variant on 17q21 is associated with age at onset and severity of asthma
E Halapi, DF Gudbjartsson, GM Jonsdottir… - European journal of …, 2010 - nature.com
A sequence variant (rs7216389-T) near the ORMDL3 gene on chromosome 17q21 was
recently found to be associated with childhood asthma. We sought to evaluate the effect of …
recently found to be associated with childhood asthma. We sought to evaluate the effect of …
Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus
Single-nucleotide polymorphisms (SNPs) in GSDMB (Gasdermin B) and ORMDL3 (ORMDL
sphingolipid biosynthesis regulator 3) are strongly associated with childhood asthma, but …
sphingolipid biosynthesis regulator 3) are strongly associated with childhood asthma, but …
Genetic and genomic approaches to asthma: new insights for the origins
Y Zhang, MF Moffatt, WOC Cookson - Current opinion in …, 2012 - journals.lww.com
Genetic and genomic approaches to asthma: new insights for t... : Current Opinion in Pulmonary
Medicine Genetic and genomic approaches to asthma: new insights for the origins : Current …
Medicine Genetic and genomic approaches to asthma: new insights for the origins : Current …
Asthma genetics 2006: the long and winding road to gene discovery
C Ober, S Hoffjan - Genes & Immunity, 2006 - nature.com
Asthma and atopy are complex phenotypes that are influenced by both genetic and
environmental factors. A review of nearly 500 papers on disease association studies …
environmental factors. A review of nearly 500 papers on disease association studies …
Genome-wide interaction analysis of air pollution exposure and childhood asthma with functional follow-up
A Gref, SK Merid, O Gruzieva, S Ballereau… - American journal of …, 2017 - atsjournals.org
Rationale: The evidence supporting an association between traffic-related air pollution
exposure and incident childhood asthma is inconsistent and may depend on genetic factors …
exposure and incident childhood asthma is inconsistent and may depend on genetic factors …
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
T Hirota, A Takahashi, M Kubo, T Tsunoda, K Tomita… - Nature …, 2011 - nature.com
Bronchial asthma is a common inflammatory disease caused by the interaction of genetic
and environmental factors,. Through a genome-wide association study and a replication …
and environmental factors,. Through a genome-wide association study and a replication …
[引用][C] GABRIEL Consortium. A large-scale, consortium-based genomewide association study of asthma
MF Moffatt - N Engl J Med, 2010