This work investigated the improvement of arterial oxygenation in hypoxic rats during
peritoneal perfusion with the oxygen-carrying perfluorocarbon blood substitute FC 43. Three …

Fluosol DA is an experimental means of supplementing oxygen delivery in the anemic
patient. The drug's ability to improve oxygen transport appears to improve SVO2. Blood …

Artificial blood for clinical use is not yet available therefore, we previously developed
artificial oxygen carriers (capsules) and showed their functionality in vitro and …

The 1980s saw a surge of interest in the develop-ment of “blood substitutes,” synthetic or
semi-synthetic materials that could deliver oxygen to tissues without the risk of infectious …

Under normal conditions, only 20–30% of the delivered oxygen is metabolised. In
normovolaemic anaemia, the organism reacts with increases in cardiac output and oxygen …

Review: Biomedical applications of perfluorinated compounds, which are either dense white
powders or colorless, odorless liquids, are based on their gas transport capabilities and …

The oxygen transport capacity of fluorocarbons was investigated in the hamster chamber
window model microcirculation to determine the rate at which oxygen is delivered to the …

Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse
events (ie, platelet activation, decreased platelet count, febrile responses, changes in …

Background To avoid unnecessary blood transfusions, physiologic transfusion triggers,
rather than exclusively hemoglobin-based transfusion triggers, have been suggested. The …