Long-term safety of approved biologics for ulcerative colitis
Introduction Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) affecting
the large intestine and carrying a heavy burden of morbidity for patients. Conventional …
the large intestine and carrying a heavy burden of morbidity for patients. Conventional …
The safety of biological pharmacotherapy for the treatment of ulcerative colitis
Introduction: Biological agents are effective in ulcerative colitis (UC). Currently, 3 anti-TNF
agents (infliximab, adalimumab, and golimumab) and 1 anti-integrin agent (vedolizumab) …
agents (infliximab, adalimumab, and golimumab) and 1 anti-integrin agent (vedolizumab) …
[HTML][HTML] The efficacy of currently licensed biologics for treatment of ulcerative colitis: a literature review
H Awan, U Fatima, R Eaw, N Knox, L Alrubaiy - Cureus, 2023 - ncbi.nlm.nih.gov
Biologics have been emerging as promising therapies in ulcerative colitis (UC) patients who
are refractory to conventional medical treatment. This literature review aims to appraise the …
are refractory to conventional medical treatment. This literature review aims to appraise the …
Safety of biological therapies in ulcerative colitis: an umbrella review of meta-analyses
S Bonovas, K Pantavou, D Evripidou… - Best practice & research …, 2018 - Elsevier
Biological agents have proven clinical efficacy in the treatment of ulcerative colitis (UC).
Their adverse effects have also been studied in a substantial number of primary studies and …
Their adverse effects have also been studied in a substantial number of primary studies and …
Safety profile of biologic drugs in the therapy of ulcerative colitis: a systematic review and network Meta‐Analysis
Objectives We compared the safety profile of biologic drugs in patients with moderately to
severely active ulcerative colitis (UC). Methods A systematic literature search was performed …
severely active ulcerative colitis (UC). Methods A systematic literature search was performed …
Biologic therapies in ulcerative colitis: primi inter pares?
M Allocca, G Fiorino, D Gilardi, P Preatoni… - Current Drug …, 2018 - ingentaconnect.com
Background: In the last decade, the introduction of the first anti-tumor necrosis factor (TNF)-α
agent infliximab has revolutionized the treatment of ulcerative colitis (UC). However, this …
agent infliximab has revolutionized the treatment of ulcerative colitis (UC). However, this …
An indirect comparison of efficacy including histologic assessment and safety in biologic therapy in ulcerative colitis: Systemic review and network meta-analysis
K Chae, YS Seo, YM Yu, MJ Chang, J Choi - Plos one, 2023 - journals.plos.org
Backgrounds and aims There are currently no studies comparing histologic remission of
FDA-approved biologics for moderate to severe ulcerative colitis (UC), except for one head …
FDA-approved biologics for moderate to severe ulcerative colitis (UC), except for one head …
Systematic review with network meta-analysis: comparative efficacy of biologics in the treatment of moderately to severely active ulcerative colitis
AD Vickers, C Ainsworth, R Mody, A Bergman… - PLoS …, 2016 - journals.plos.org
Background Biological therapies are increasingly used to treat ulcerative colitis (UC). Aim To
compare the efficacy of biologics in adults with moderately-to-severely active UC, stratified …
compare the efficacy of biologics in adults with moderately-to-severely active UC, stratified …
Evaluating study withdrawal among biologics and immunomodulators in treating ulcerative colitis: a meta-analysis of controlled clinical trials
ED Shah, CA Siegel, K Chong… - Inflammatory Bowel …, 2016 - academic.oup.com
Background We conducted a systematic review and meta-analysis to evaluate the efficacy
and adverse event (AE)-associated tolerability of treatment with immunomodulators and …
and adverse event (AE)-associated tolerability of treatment with immunomodulators and …
The long-term effect of biologics in patients with ulcerative colitis emerging from a large Japanese cohort
Y Yokoyama, Y Ohta, S Ogasawara, J Kato, R Arai… - Scientific Reports, 2022 - nature.com
To gain a better understanding of the effects of biologics, we evaluated clinical outcomes in
patients with moderate to severe exacerbations of ulcerative colitis (UC). This retrospective …
patients with moderate to severe exacerbations of ulcerative colitis (UC). This retrospective …