Background: The urinary sodium-potassium ratio (Na-K ratio) has recently been regarded as
another hypertension indicator. The current study aims to assess the association of urine …

The association between salt intake and renal outcome in subjects with preserved kidney
function remains unclear. Here we evaluated the effect of sodium intake on the development …

The interindividual variability of the blood pressure response to changes in dietary sodium
intake might be traced in part to heterogeneity in renal adaptation. To further explore this …

Evidence suggests that increased salt consumption induces blood pressure‐(BP) mediated
organ damage, yet it remains unclear whether it reflects a generalized micro‐and …

Age-related changes in blood pressure, renal function, and sodium homeostasis suggest
that sodium sensitivity of blood pressure may also be influenced by age. Blood pressure was …

Increased intrarenal vascular resistance is suggested to accompany chronic kidney
diseases (CKD), which is known to be closely associated with hypertension. However, there …

The pathophysiology of hypertension, which affects over 1 billion individuals worldwide,
involves the integration of the actions of multiple organ systems, including the kidney. The …

Little is known about the population genetics of water balance. A recent meta-genome-wide
association study on plasma sodium concentration identified novel loci of high biological …

Initially, the renal resistive index (RRI) was investigated with the aim of improving diagnosis
in kidney diseases, but this goal was not met. Recently, many papers have highlighted the …

We thank Dr Heine et al1 for their interest in our recent findings2, 3 and for their crucial and
constructive criticisms and comments concerning the renal resistive index (RI). In response …