Angiogenesis, the growth of neovasculature from pre-existing vessels, is driven by the
stimulation of endothelial cells (ECs) by pro-angiogenic factors to invade the surrounding …

The ability to form a variety of cell‐matrix connections is crucial for angiogenesis to take
place. Without stable anchorage to the extracellular matrix (ECM), endothelial cells (ECs) …

Angiogenesis relies on the ability of endothelial cells (ECs) to migrate over the extracellular
matrix via integrin receptors to respond to an angiogenic stimulus. Of the two neuropilin …

In development and disease, vascular endothelial growth factor (VEGF) regulates the
expansion of the vascular tree. In response to hypoxia, VEGF promotes new capillary …

Angiogenesis is the process by which new vessels form from pre-existing vasculature and is
a crucial process during embryogenesis. However, dysregulation of angiogenesis can lead …

During development, tissue repair, and tumor growth, most blood vessel networks are
generated through angiogenesis. Vascular endothelial growth factor (VEGF) is a key …

Blood vessel formation during vertebrate development relies on a process called
angiogenesis and is essential for organ growth and tissue viability. In addition, angiogenesis …

Although a number of studies have focused on the role of neuropilin-2 (NRP2) in early
embryological development and in various cancer cells, very little is known about the …

The formation of the cardiovasculature, consisting of both the heart and blood vessels, is a
critical step in embryonic development and relies on three processes termed …

Purpose: Neuropilin-1 (NRP-1) is a transmembrane receptor that is critical for vascular
development within the central nervous system (CNS). It binds and influences signaling of …