Human recombinant chromogranin A-derived vasostatin-1 mimics preconditioning via an adenosine/nitric oxide signaling mechanism
S Cappello, T Angelone, B Tota… - American Journal …, 2007 - journals.physiology.org
The acidic protein chromogranin A (CgA) is the precursor of several regulatory peptides
generated by specific proteolytic processes. Human recombinant CgA NH2-terminal …
generated by specific proteolytic processes. Human recombinant CgA NH2-terminal …
The homologous rat chromogranin A1‐64 (rCGA1‐64) modulates myocardial and coronary function in rat heart to counteract adrenergic stimulation indirectly via …
Chromogranin A (CGA), produced by human and rat myocardium, generates several
biologically active peptides processed at specific proteolytic cleavage sites. A highly …
biologically active peptides processed at specific proteolytic cleavage sites. A highly …
Recombinant N–terminal fragments of chromogranin–a modulate cardiac function of the Langendorff–perfused rat heart
In this study we tested the hypothesis that vasostatins could act as myocardial modulators in
the mammalian heart. Using the Langendorff–perfused rat heart, the cardiac effects of the …
the mammalian heart. Using the Langendorff–perfused rat heart, the cardiac effects of the …
The interplay between chromogranin A-derived peptides and cardiac natriuretic peptides in cardioprotection against catecholamine-evoked stress
Chromogranin A (CgA) is the major soluble protein co-stored and co-released with
catecholamines (CAs) from secretory vesicles in the adrenal medulla chromaffin cells …
catecholamines (CAs) from secretory vesicles in the adrenal medulla chromaffin cells …
Cardioprotection Against Ischemia/Reperfusion Injury and Chromogranin ADerived Peptides
C Penna, F Tullio, MG Perrelli… - Current medicinal …, 2012 - ingentaconnect.com
Chromogranin A (CgA) is produced by cells of the sympathoadrenal system and by human
ventricular myocardium. In the clinical setting CgA has been mainly used as a marker of …
ventricular myocardium. In the clinical setting CgA has been mainly used as a marker of …
Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function
Abstract Aims High chromogranin-A (CgA) levels were observed in patients with heart failure
but its source remained uncertain. We evaluated whether CgA is produced by myocardium …
but its source remained uncertain. We evaluated whether CgA is produced by myocardium …
Cytoskeleton mediates negative inotropism and lusitropism of chromogranin A-derived peptides (human vasostatin1-78 and rat CgA1-64) in the rat heart
Cytoskeleton scaffold in cardiac myocytes provides structural support and
compartmentalization of intracellular components. It is implicated in cardiac pathologies …
compartmentalization of intracellular components. It is implicated in cardiac pathologies …
Endothelium dependent cardiovascular effects of the chromogranin A-derived peptides vasostatin-1 and catestatin
S Fornero, E Bassino, MP Gallo… - Current medicinal …, 2012 - ingentaconnect.com
The involvement of Chromogranin A (CgA) in the cardiovascular function regulation is
attributed to its function as a prohormone. Several studies indicated that CgA-derived …
attributed to its function as a prohormone. Several studies indicated that CgA-derived …
Full-length human chromogranin-A cardioactivity: myocardial, coronary, and stimulus-induced processing evidence in normotensive and hypertensive male rat hearts
Plasma chromogranin-A (CgA) concentrations correlate with severe cardiovascular
diseases, whereas CgA-derived vasostatin-I and catestatin elicit cardiosuppression via an …
diseases, whereas CgA-derived vasostatin-I and catestatin elicit cardiosuppression via an …
The chromogranin A-derived peptides vasostatin-I and catestatin as regulatory peptides for cardiovascular functions
KB Helle - Cardiovascular research, 2010 - academic.oup.com
A range of inflammatory conditions is associated with pathologically high levels of circulating
chromogranin A (CgA). This prohormone belongs to the family of uniquely acidic proteins co …
chromogranin A (CgA). This prohormone belongs to the family of uniquely acidic proteins co …