Mechanotransduction: a major regulator of homeostasis and development

KS Kolahi, MRK Mofrad - Wiley Interdisciplinary Reviews …, 2010 - Wiley Online Library
In nearly all aspects of biology, forces are a relevant regulator of life's form and function.
More recently, science has established that cells are exquisitely sensitive to forces of varying …

Mechanotransduction: use the force (s)

EK Paluch, CM Nelson, N Biais, B Fabry, J Moeller… - BMC biology, 2015 - Springer
Mechanotransduction-how cells sense physical forces and translate them into biochemical
and biological responses-is a vibrant and rapidly-progressing field, and is important for a …

Signalling through mechanical inputs–a coordinated process

H Zhang, M Labouesse - Journal of cell science, 2012 - journals.biologists.com
There is growing awareness that mechanical forces–in parallel to electrical or chemical
inputs–have a central role in driving development and influencing the outcome of many …

Review of cellular mechanotransduction

N Wang - Journal of physics D: Applied physics, 2017 - iopscience.iop.org
Living cells and tissues experience physical forces and chemical stimuli in the human body.
The process of converting mechanical forces into biochemical activities and gene …

Mechano-transduction: from molecules to tissues

BL Pruitt, AR Dunn, WI Weis, WJ Nelson - PLoS biology, 2014 - journals.plos.org
External forces play complex roles in cell organization, fate, and homeostasis. Changes in
these forces, or how cells respond to them, can result in abnormal embryonic development …

Mechanotransduction and its role in stem cell biology

CB Wolf, MRK Mofrad - Trends in stem cell biology and technology, 2009 - Springer
Most cells can sense and actively respond to mechanical stimuli. Yet the exact processes
that convert mechanical signals into a cascade of biochemical signals that affect the …

Feeling the force: multiscale force sensing and transduction at the cell-cell interface

A Inman, M Smutny - Seminars in Cell & Developmental Biology, 2021 - Elsevier
A universal principle of all living cells is the ability to sense and respond to mechanical
stimuli which is essential for many biological processes. Recent efforts have identified …

[HTML][HTML] Decoding mechanical cues by molecular mechanotransduction

V Swaminathan, M Gloerich - Current opinion in cell biology, 2021 - Elsevier
Cells are exposed to a variety of mechanical cues, including forces from their local
environment and physical properties of the tissue. These mechanical cues regulate a vast …

[图书][B] Mechanobiology handbook

J Nagatomi, EE Ebong - 2011 - api.taylorfrancis.com
The initial concept for Mechanobiology Handbook spawned from the insightful vision of a
CRC Press editor, Michael Slaughter, who found potential in the growth of this field and took …

Steps in mechanotransduction pathways that control cell morphology

H Wolfenson, B Yang, MP Sheetz - Annual review of physiology, 2019 - annualreviews.org
It is increasingly clear that mechanotransduction pathways play important roles in regulating
fundamental cellular functions. Of the basic mechanical functions, the determination of …