Conditional deletion of Hspa5 leads to spermatogenesis failure and male infertility in mice
Z Wen, H Zhu, J Wang, B Wu, A Zhang, H Zhao… - Life Sciences, 2023 - Elsevier
Heat shock proteins (HSPs) have important roles in different developmental stages of
spermatogenesis. The heat shock 70 kDa protein 5 (HSPA5) is an important component of …
spermatogenesis. The heat shock 70 kDa protein 5 (HSPA5) is an important component of …
[HTML][HTML] The heat shock protein family gene Hspa1l in male mice is dispensable for fertility
X Wang, W Xie, Y Yao, Y Zhu, J Zhou, Y Cui, X Guo… - PeerJ, 2020 - peerj.com
Background Heat shock protein family A member 1 like (Hspa1l) is a member of the 70kD
heat shock protein (Hsp70) family. HSPA1L is an ancient, evolutionarily conserved gene …
heat shock protein (Hsp70) family. HSPA1L is an ancient, evolutionarily conserved gene …
Heat-shock protein HSPA4 is required for progression of spermatogenesis
T Held, AZ Barakat, BA Mohamed, I Paprotta… - …, 2011 - rep.bioscientifica.com
Abstract Heat-shock protein 110 (HSP110) family members act as nucleotide exchange
factors (NEF) of mammalian and yeast HSP70 chaperones during the ATP hydrolysis cycle …
factors (NEF) of mammalian and yeast HSP70 chaperones during the ATP hydrolysis cycle …
Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development
T Held, I Paprotta, J Khulan… - … and Cellular Biology, 2006 - Am Soc Microbiol
The Hspa4l gene, also known as Apg1 or Osp94, belongs to the HSP110 heat shock gene
family, which includes three genes encoding highly conserved proteins. This study shows …
family, which includes three genes encoding highly conserved proteins. This study shows …
Heat shock protein A2 (HSPA2): Regulatory roles in germ cell development and sperm function
Among the numerous families of heat shock protein (HSP) that have been implicated in the
regulation of reproductive system development and function, those belonging to the 70 kDa …
regulation of reproductive system development and function, those belonging to the 70 kDa …
Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse
EG Bromfield, RJ Aitken… - MHR: Basic science of …, 2017 - academic.oup.com
STUDY QUESTION Does oxidative stress compromise the protein expression of heat shock
protein A2 (HSPA2) in the developing germ cells of the mouse testis? SUMMARY ANSWER …
protein A2 (HSPA2) in the developing germ cells of the mouse testis? SUMMARY ANSWER …
Decreased expression of heat shock protein A4L in spermatozoa is positively related to poor human sperm quality
XX Liu, X Wang, FJ Liu - Molecular Reproduction and …, 2019 - Wiley Online Library
Heat shock protein A4L (HSPA4L), which is highly expressed in the testis, is correlated with
male fertility. However, the relationship between HSPA4L expression and sperm quality …
male fertility. However, the relationship between HSPA4L expression and sperm quality …
The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition
One of the most common lesions present in the spermatozoa of human infertility patients is
an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can …
an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can …
Depression of HspA2 in human testis is associated with spermatogenic impairment and fertilization rate in ICSI treatment for azoospermic individuals
Y Tian, F Zhang, X Zhang, L Li, L Wang, B Shi… - Journal of assisted …, 2014 - Springer
Purpose Heat shock protein A2 (HspA2) expression was quantitatively measured in human
testis and its relationship with the spermatogenetic status and laboratory outcomes of …
testis and its relationship with the spermatogenetic status and laboratory outcomes of …
MAPKAP kinase 2–mediated phosphorylation of HspA1L protects male germ cells from heat stress–induced apoptosis
PA Williams, HE Kobilnyk, EA McMillan… - Cell Stress and …, 2019 - Springer
Developing male germ cells are extremely sensitive to heat stress; consequently, anatomic
and physiologic adaptations have evolved to maintain proper thermoregulation during …
and physiologic adaptations have evolved to maintain proper thermoregulation during …