The role of heat shock proteins in reproductive system development and function

DJ MacPhee - 2017 - Springer
Heat shock proteins (HSPs) are a large family of very conserved proteins with important
roles in cellular homeostasis and cytoprotection from chronic or acute stressors. As …

[PDF][PDF] Role of heat shock protein HSP70-2 in spermatogenesis

EM Eddy - Reviews of reproduction, 1999 - scholar.archive.org
The HSP70 heat-shock proteins are molecular chaperones that assist other proteins in their
folding, transport and assembly into complexes. Most of these proteins are either …

[HTML][HTML] RNA polymerase II interacts with the Hspa1b promoter in mouse epididymal spermatozoa

DC Wilkerson, KD Sarge - Reproduction (Cambridge, England), 2009 - ncbi.nlm.nih.gov
Abstract The Hspa1b (Hsp70. 1) gene is one of the first genes expressed after fertilization,
with expression occurring during the minor zygotic genome activation in the absence of …

Post-meiotic shifts in HSPA2/HSP70. 2 chaperone activity during mouse spermatogenesis

J Govin, C Caron, E Escoffier, M Ferro, L Kuhn… - Journal of Biological …, 2006 - ASBMB
HSPA2 (formerly HSP70. 2) is a testis-specific member of the HSP70 family known to play a
critical role in the completion of meiosis during male germ cell differentiation. Although …

Effect of heat shock transcription factor 5 (Hsf5) knockdown on heat shock family in mouse Leydig cells and Sertoli cells

L ZHONG, H ZHONG, Y DAI… - Basic & Clinical …, 2023 - journal11.magtechjournal.com
Objective To investigate the effect of knockdown heat shock transcription factor 5 (Hsf5) on
the expression of heat shock family in mouse Leydig cells (TM3) and Sertoli cells (TM4) …

Paternal factors in recurrent pregnancy loss: an insight through analysis of non-synonymous single-nucleotide polymorphism in human testis-specific chaperone …

G Mohanty, SR Jena, S Kar, L Samanta - Environmental Science and …, 2021 - Springer
Heat shock protein A2 (HSPA2) is a testis-specific molecular chaperone of the 70 kDa heat
shock protein (HSP70) family and reported to play a key role in spermatogenesis as well as …

Heat shock transcription factor 1 is involved in quality-control mechanisms in male germ cells

H Izu, S Inouye, M Fujimoto, K Shiraishi… - Biology of …, 2004 - academic.oup.com
Quality-control mechanisms in spermatogenesis are important to eliminate injured or
abnormal cells, thereby protecting the organism from abnormal development in the next …

Acute mild heat stress alters gene expression in testes and reduces sperm quality in mice

G Rizzoto, G Boe-Hansen, C Klein, JC Thundathil… - Theriogenology, 2020 - Elsevier
Heat stress is a major concern in animal reproduction, as testicular temperature must be 3–
5° C below body core temperature for production of motile and fertile sperm in mammals …

Interaction of HSF1 and HSF2 with the Hspa1b Promoter in Mouse Epididymal Spermatozoa

DC Wilkerson, LA Murphy, KD Sarge - Biology of reproduction, 2008 - academic.oup.com
The Hspa1b gene is one of the first genes expressed after fertilization, with expression
observed in the male pronucleus as early as the one-cell stage of embryogenesis. This …

Testis-enriched heat shock protein A2 (HSPA2): Adaptive advantages of the birds with internal testes over the mammals with testicular descent

A Padhi, MM Ghaly, L Ma - Scientific Reports, 2016 - nature.com
The molecular chaperone heat shock protein A2 (HSPA2), a member of the 70 kDa heat
shock protein (HSP70) family, plays an important role in spermatogenesis and male fertility …