Alternatives to nasopharyngeal sampling are needed to increase capacity for SARS-CoV-2
testing. Among 275 participants, we piloted the collection of nasal mid-turbinate swabs …

Developing and deploying new diagnostic tests are difficult, but the need to do so in
response to a rapidly emerging pandemic such as COVID-19 is crucially important. During a …

A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. Since the onset of …

In SARS-CoV-2 diagnostics, cycle threshold (Ct) values from qRT-PCRs semi-quantitatively
estimate a patient's viral load. However, relevant analytical differences between qRT-PCR …

To the Editor, Timely and rapid diagnosis of severe acute respiratory syndrome coronavirus
2 (SARS‐CoV‐2) infection by reverse transcription‐polymerase chain reaction (RT‐PCR) is …

Real-time reverse transcription polymerase chain reaction (RT-qPCR) is the most sensitive
and specific assay and, therefore, is the “gold standard” diagnostic method for the diagnosis …

The current scale of public and private testing cannot be expected to meet the emerging
need for higher levels of community-level and repeated screening of asymptomatic …

To combat the COVID‐19 pandemic, millions of PCR tests are performed worldwide. Any
deviation of the diagnostic sensitivity and specificity will reduce the predictive values of the …

The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
exemplifies the critical need for accurate and rapid diagnostic assays to prompt clinical and …

Abstract Background The ongoing SARS-CoV-2 pandemic presents a unique challenge to
diagnostic laboratories. There are preliminary studies correlating qRT-PCR results from …