B cells require signals from multiple sources for their development from precursor cells, and
differentiation into effector cells. BAFF has been identified as a critical regulator of B cell …

BAFF [B‐cell activating factor belonging to the tumor necrosis factor (TNF) family] is a ligand
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …

The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …

The TNF family member BAFF is a fundamental survival factor for B cells. BAFF binds to
three receptors, only one of which, BAFF-R, does not cross-react with the BAFF-related …

BAFF (B lymphocyte activating factor of the tumour necrosis factor family) is a vital
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …

BAFF is a key factor controlling B cell survival and maturation and its over-expression
promotes B cell-mediated autoimmune disorders and participates in the progression of B …

BAFF, a member of the TNF family, is a fundamental survival factor for transitional and
mature B cells. BAFF overexpression leads to an expanded B cell compartment and …

BAFF, APRIL and their receptors play important immunological roles, especially in the B cell
arm of the immune system. A number of splice isoforms have been described for both …

Interactions of BAFF (B-cell activating factor) with BAFF-R, one of three BAFF-binding
receptors that are preferentially expressed on B cells, are essential for B-cell development …

The TNF family member protein BAFF/BLyS is essential for B cell survival and plays an
important role in regulating class switch recombination as well as in the selection of …