Formulation and optimization of rivastigmine-loaded PLGA and chitosan nanoparticles for transdermal delivery

S Priya, CL Lobo - Research Journal of Pharmacy and …, 2023 - indianjournals.com
Rivastigmine (RVT) is anti-Alzheimer with low bioavailability and with short elimination half-
life due to significant first-pass metabolism. RVT is a hydrophilic drug because it has low …

[PDF][PDF] Optimization of rivastigmine chitosan nanoparticles for neurodegenerative Alzheimer; in vitro and ex vivo characterizations

MI El-Assal, D Samuel - Int J Pharm Pharm Sci, 2022 - academia.edu
Objective: In an attempt to optimize the anti-Alzheimer effect, rivastigmine-loaded chitosan
nanoparticles were developed in order to target of brain through skin permeation. Methods …

[HTML][HTML] Preparation and characterization of rivastigmine transdermal patch based on chitosan microparticles

M Sadeghi, F Ganji, SM Taghizadeh… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Here we report a novel approach for preparation of a 6-day transdermal drug delivery
system (TDDS) as treatment for mild to moderate Alzheimer's disease. The spray drying …

[PDF][PDF] Development and evaluation of transdermal film containing solid lipid nanoparticles of rivastigmine tartrate

G Ravi, NV Gupta - Int J Appl Pharm, 2017 - academia.edu
Objective: The objective of present investigation was to develop rivastigmine tartrate
transdermal film employing factorial design. Methods: The formulations were designed by …

[HTML][HTML] Formulation and characterization of polymeric nanoparticle of Rivastigmine for effective management of Alzheimer's disease

F Imam, S Mukhopadhyay, P Kothiyal, S Alshehri… - Saudi Pharmaceutical …, 2024 - Elsevier
Memory loss or dementia is a progressive disorder, and one of its common forms is
Alzheimer's disease (AD), effecting mostly middle aged and older adults. In the present …

[PDF][PDF] Preparation and characterization of rivastigmine loaded chitosan nanoparticles

S preet Kaur, R Rao, A Hussain, S Khatkar - Journal of pharmaceutical …, 2011 - Citeseer
Nanotechnology mediated drug delivery has been reported to enhance the drug efficacy,
bioavailability, reduce toxicity and improve patient compliance by targeting the cells and …

Novel L-Lactide-depsipeptide polymeric carrier for enhanced brain uptake of rivastigmine in treatment of Alzheimer's disease

KP Pagar, SM Sardar, PR Vavia - Journal of biomedical …, 2014 - ingentaconnect.com
The present study discusses possibility of targeting an anti-Alzheimer's drug rivastigmine
tartarate (RT) to the brain using novel synthesized L-lactide-depsipeptide polymeric …

Rivastigmine Loaded PEG-PLGA Nanoparticles for Enhanced Delivery to the Brain: In-Vitro and In-Vivo Studies for Alzheimer's disease

J Prakash, VV Prasad, A Claret - 2022 - researchsquare.com
Purpose Rivastigmine Tartrate (RT) is a reversible cholinesterase inhibitor used for the
treatment of Alzheimer's disease and CNS disorder. The entry of the drug to the brain is …

Optimization and charaterization of repaglinide biodegradable polymeric nanoparticle loaded transdermal patchs: In vitro and in vivo studies

V Vijayan, KR Reddy, S Sakthivel, C Swetha - Colloids and Surfaces B …, 2013 - Elsevier
Biodegradable polymeric nanoparticles loaded Repaglinide were prepared by solvent
extraction method. In this method chitosan, PLA and PCL were employed to prepare …

[PDF][PDF] Terbinafine hydrochloride loaded PLGA nanoparticles for topical administration

S Rençber, ST Tanrıverdi - Proceedings of the 3rd World Congress on …, 2018 - avestia.com
Terbinafine hydrochloride (TBF-HCl) loaded poly (lactic-co-glycolic acid)(PLGA)
nanoparticles (NPs) were produced by emulsification/solvent evaporation method and were …