We studied superoxide dismutases (SODs) in the encapsulated yeast Cryptococcus
neoformans (Cn) variety gattii to analyse the role of mitochondrial MnSOD (SOD2) in fungal …

The pathogenic yeast Cryptococcus neoformans (Cn) var. gattii causes meningoencephalitis
in healthy individuals, unlike the better known Cn varieties grubii and neoformans, which are …

Superoxide dismutase (SOD) is an enzyme that converts superoxide radicals into hydrogen
peroxide and molecular oxygen and has been shown to contribute to the virulence of many …

Manganese superoxide dismutase is an essential component of the mitochondrial
antioxidant defense system of most eukaryotes. In the present study, we used a reverse …

Cryptococcus neoformans is a fungal pathogen most commonly causing meningitis in
immunocompromised patients. Current therapies are inadequate, and novel antifungal …

Cryptococcusneoformans (Cn), causal agent of fungal meningoencephalitis, has three
varieties with variable host predilection. To explore mechanisms for these pathogenic …

We identified a homologue of the alternative oxidase gene in a screen to identify genes that
are preferentially transcribed in response to a shift to 37° C in the human-pathogenic yeast …

Glutathione peroxidases catalyse the reduction of peroxides by reduced glutathione. To
determine if these enzymes are important for resistance to oxidative stress and evasion of …

The ability of the fungal pathogen Cryptococcus neoformans to evade the mammalian innate
immune response and cause disease is partially due to its ability to respond to and survive …

Cryptococcus neoformans is an opportunistic pathogen and the leading cause of fungal
meningitis. To survive within the host, this organism must be able to protect itself from …