Inhaled corticosteroid use by exacerbations and eosinophils: a real-world COPD population

J Vestbo, CF Vogelmeier, M Small… - … Journal of Chronic …, 2019 - Taylor & Francis
Background: Blood eosinophils may predict response to inhaled corticosteroids (ICS) in
chronic obstructive pulmonary disease (COPD) where ICS is recommended in patients at …

Blood eosinophil counts, withdrawal of inhaled corticosteroids and risk of COPD exacerbations and mortality in the Clinical Practice Research Datalink (CPRD)

OA Oshagbemi, FME Franssen… - COPD: Journal of …, 2019 - Taylor & Francis
Although recently introduced in the pharmacological treatment algorithm of chronic
obstructive pulmonary disease (COPD), there is a need for more data supporting the use of …

[HTML][HTML] In 'real world'patients with COPD, exacerbation history, and not blood eosinophils, is the most reliable predictor of future exacerbations

H Worth, R Buhl, CP Criée, P Kardos, E Gückel… - Respiratory …, 2023 - Springer
Introduction There is an interest in the role of blood eosinophils for predicting inhaled
corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data …

[HTML][HTML] Blood eosinophils to guide inhaled maintenance therapy in a primary care COPD population

HF Ashdown, M Smith, E McFadden… - ERJ Open …, 2022 - Eur Respiratory Soc
Blood eosinophils are a potentially useful biomarker for guiding inhaled corticosteroid (ICS)
treatment decisions in COPD. We investigated whether existing blood eosinophil counts …

Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the …

H Watz, K Tetzlaff, EFM Wouters, A Kirsten… - The lancet Respiratory …, 2016 - thelancet.com
Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …

Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality

OA Oshagbemi, FME Franssen… - … and drug safety, 2018 - Wiley Online Library
Purpose It remains unclear whether eosinophilia is useful for in guiding inhaled
corticosteroid (ICS) therapy in chronic obstructive pulmonary disease (COPD) patients. The …

[HTML][HTML] A systematic review of blood eosinophils and continued treatment with inhaled corticosteroids in patients with COPD

DA Dalin, A Løkke, P Kristiansen, C Jensen… - Respiratory …, 2022 - Elsevier
Inhaled corticosteroid (ICS) in patients with chronic obstructive pulmonary disease (COPD)
has been debated for 20 years. In our systematic literature review and meta-analysis, we …

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD

NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …

The association between eosinophil variability patterns and the efficacy of inhaled corticosteroids in stable COPD patients

JK Yoon, JK Lee, CH Lee, YI Hwang… - … Journal of Chronic …, 2020 - Taylor & Francis
Introduction Blood eosinophils are a predictive marker for the use of inhaled corticosteroids
(ICS). However, there is concern over whether a single measure of blood eosinophils is …

Blood eosinophils and inhaled corticosteroids in patients with COPD: systematic review and meta-analysis

SL Cheng - International journal of chronic obstructive pulmonary …, 2018 - Taylor & Francis
Background COPD is a highly heterogeneous disease. Potential biomarkers to identify
patients with COPD who will derive the greatest benefit from inhaled corticosteroid (ICS) …