[HTML][HTML] C-reactive protein levels predict responses to PD-1 inhibitors in hepatocellular carcinoma patients

Y Zhang, L Lu, Z He, Z Xu, Z Xiang, RC Nie… - Frontiers in …, 2022 - frontiersin.org
Background Serum C-reactive protein (CRP) is a biomarker of an acute inflammatory
response and has been successfully used as a prognostic predictor for several …

[HTML][HTML] Reductions in AFP and PIVKA-II can predict the efficiency of anti-PD-1 immunotherapy in HCC patients

X Sun, J Mei, W Lin, Z Yang, W Peng, J Chen, Y Zhang… - BMC cancer, 2021 - Springer
Background Few biomarkers can predict the efficiency of PD-1 blockade in patients with
hepatocellular carcinoma (HCC). This study aimed to investigate the prognostic role of AFP …

[HTML][HTML] Could we predict the response of immune checkpoint inhibitor treatment in hepatocellular carcinoma?

C Lee, SL Chan, HJ Chon - Cancers, 2022 - mdpi.com
Simple Summary The use of anti-programmed cell-death protein (ligand)-1 (PD-[L] 1) is now
a standard of care for treating hepatocellular carcinoma (HCC). However, the treatment only …

Comparison of the prognostic value of inflammation-based scores in patients with hepatocellular carcinoma after anti-PD-1 therapy

J Mei, XQ Sun, WP Lin, SH Li, LH Lu… - Journal of …, 2021 - Taylor & Francis
Background Inflammatory response is related to cancer progression and patient survival.
However, the value in predicting survival in hepatocellular carcinoma (HCC) patients who …

Association of the pretreatment lung immune prognostic index with survival outcomes in advanced hepatocellular carcinoma patients treated with PD-1 inhibitors

S Chen, Z Huang, W Jia, H Tao, S Zhang… - Journal of …, 2020 - Taylor & Francis
Purpose At present, there are no validated biomarkers that can predict whether patients with
advanced hepatocellular carcinoma (aHCC) are likely to benefit from anti-PD-1 therapy. We …

[HTML][HTML] C-reactive protein is an indicator of the immunosuppressive microenvironment fostered by myeloid cells in hepatocellular carcinoma

Y Wang, Z Li, Z Huang, X Yu, L Zheng, J Xu - Frontiers in Oncology, 2022 - frontiersin.org
Background C-reactive protein (CRP) is a widely used marker of systemic inflammation and
predicts poor clinical outcomes in patients with hepatocellular carcinoma (HCC); however …

[HTML][HTML] Response Evaluation and Survival Prediction Following PD‐1 Inhibitor in Patients With Advanced Hepatocellular Carcinoma: Comparison of the RECIST 1.1 …

M Zhou, C Zhang, J Nie, Y Sun, Y Xu, F Wu… - Frontiers in …, 2021 - frontiersin.org
Background Precise evaluation of the efficacy of immunotherapy is critical in the effective
management and treatment of advanced hepatocellular carcinoma (HCC). Therefore, the …

Blood Biomarkers Predict Survival Outcomes in Patients with Hepatitis B Virus‐Induced Hepatocellular Carcinoma Treated with PD‐1 Inhibitors

R Huang, Y Zheng, W Zou, C Liu… - Journal of Immunology …, 2022 - Wiley Online Library
Purpose. To investigate the prognostic value of blood markers in patients with hepatitis B
virus (HBV)‐induced hepatocellular carcinoma (HCC) treated with PD‐1 inhibitors. Patients …

Prognostic value of inflammation‐immunity‐nutrition score in patients with hepatocellular carcinoma treated with anti‐PD‐1 therapy

Z Zhang, Y Liang, D Zhong, Z Dai… - Journal of Clinical …, 2022 - Wiley Online Library
Background There are no validated biomarkers that can predict the clinical benefit of
immune checkpoint blockers against the programmed cell death protein 1 (PD‐1) treatments …

Immune‐related adverse events predict responses to PD‐1 blockade immunotherapy in hepatocellular carcinoma

L Lu, K Xing, W Wei, Y Ling, P Li, S Li… - … Journal of Cancer, 2021 - Wiley Online Library
Immune checkpoint blockade has demonstrated remarkable efficacy in hepatocellular
carcinoma (HCC) but is also commonly accompanied by immune‐related adverse events …