Association of rs2072446 in the NGFR gene with the risk of Alzheimer's disease and amyloid‐β deposition in the brain

CY He, ZT Wang, YY Shen, AY Shi… - CNS Neuroscience …, 2022 - Wiley Online Library
Abstract Introduction and Aims Alzheimer's disease (AD) is the most common form of
dementia with a complex genetic background. The cause of sporadic AD (sAD) remains …

[HTML][HTML] Genetic polymorphisms of nerve growth factor receptor (NGFR) and the risk of Alzheimer's disease

HC Cheng, Y Sun, LC Lai, SY Chen, WC Lee… - Journal of Negative …, 2012 - Springer
Background Loss of basal forebrain cholinergic neurons is attributable to the proapoptotic
signaling induced by nerve growth factor receptor (NGFR) and may link to Alzheimer's …

Genetic association between neurotrophin-3 polymorphisms and Alzheimer's disease in Japanese patients

T Nagata, N Shibata, S Shinagawa… - Dementia and Geriatric …, 2013 - karger.com
Background: Some polymorphisms of the neurotrophin family have previously been
investigated as candidate genes for Alzheimer's disease (AD). In the present study, we …

Possible influence of a non-synonymous polymorphism located in the NGF precursor on susceptibility to late-onset Alzheimer's disease and mild cognitive impairment

E Di Maria, E Giorgio, V Uliana… - Journal of …, 2012 - content.iospress.com
The complex network of neurotrophic factors is proposed to play a role in
neurodegeneration, but the effect of variations in their coding genes on susceptibility to …

SNPs in neurotrophin system genes and Alzheimer's disease in an Italian population

A Cozza, E Melissari, P Iacopetti… - Journal of …, 2008 - content.iospress.com
Increasing evidence suggests a role for nerve growth factor (NGFB), brain-derived
neurotrophic factor (BDNF), and their receptors, nerve growth factor receptor (NGFR), and …

[HTML][HTML] Association of rs6265 and rs2030324 polymorphisms in brain-derived neurotrophic factor gene with Alzheimer's disease: a meta-analysis

Y Lin, S Cheng, Z Xie, D Zhang - PLoS One, 2014 - journals.plos.org
Background The association between polymorphisms rs6265 and rs2030324 in brain-
derived neurotrophic factor (BDNF) and Alzheimer's disease (AD) has been widely reported …

Gender-related association of brain-derived neurotrophic factor gene 196A/G polymorphism with Alzheimer's disease—a meta-analysis including 6854 cases and …

J Chen, X Liang, B Li, X Jiang, Z Xu - International Journal of …, 2014 - Taylor & Francis
Epidemiological studies have evaluated the associations between brain-derived
neurotrophic factor (BDNF) 196A/G gene polymorphism and Alzheimer's disease (AD) risk …

Polymorphisms of the neurotrophic factor-3 (NTF-3) in Alzheimer's disease: rs6332 associated with onset time and rs6489630 T allele exhibited a protective role

M Liu, YR Huo, J Wang, S Liu, S Liu… - Journal of …, 2015 - Taylor & Francis
Because of its implications in neuroprotection, formation of long lasting memories and a
disturbed function in Alzheimer's disease (AD), neurotrophin-3 (NTF-3) may represent an …

NRG3 gene is associated with the risk and age at onset of Alzheimer disease

KS Wang, N Xu, L Wang, L Aragon, R Ciubuc… - Journal of neural …, 2014 - Springer
Abstract The Neuregulin 3 (NRG3) gene at 10q22–q24 has been implicated in multiple
psychiatric traits such as cognitive impairment. We therefore hypothesized that NRG3 gene …

Female-specific effect of the BDNF gene on Alzheimer's disease

GD Li, R Bi, DF Zhang, M Xu, R Luo, D Wang… - Neurobiology of …, 2017 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease influenced by
genetic and environmental factors. Brain-derived neurotrophic factor (BDNF) plays an …