Biochemical markers of muscular dystrophy

IV Seniuk, B Yassine - 2023 - dspace.nuph.edu.ua
Muscular dystrophies are characterized by a progressive loss of muscle tissue and/or
muscle function. While metabolic alterations have been described in patients' derived …

Cross‐sectional serum metabolomic study of multiple forms of muscular dystrophy

P Spitali, K Hettne, R Tsonaka, E Sabir… - Journal of Cellular …, 2018 - Wiley Online Library
Muscular dystrophies are characterized by a progressive loss of muscle tissue and/or
muscle function. While metabolic alterations have been described in patients'‐derived …

Metabolic status of patients with muscular dystrophy in early phase of the disease: in vitro, high resolution NMR spectroscopy based metabolomics analysis of serum

NK Srivastava, S Annarao, N Sinha - Life sciences, 2016 - Elsevier
Abstract Aims Proton Nuclear Magnetic Resonance (NMR) based metabolomics analysis is
extensively used to explore the metabolic profiling of biofluids. This approach was used for …

Advances in Metabolic Profiling of Biological Samples

J Pinto - Metabolites, 2023 - mdpi.com
Metabolomics constitutes a promising approach to clinical diagnostics, but its practical
implementation in clinical settings is hindered by the requirement for rapid and efficient …

Circulating biomarkers in muscular dystrophies: disease and therapy monitoring

A Koutsoulidou, LA Phylactou - Molecular Therapy Methods & Clinical …, 2020 - cell.com
Muscular dystrophies are a group of inherited disorders that primarily affect the muscle
tissues. Across the muscular dystrophies, symptoms commonly compromise the quality of …

Analysis of skeletal muscle metabolome: Evaluation of extraction methods for targeted metabolite quantification using liquid chromatography tandem mass …

R El Rammouz, F Létisse, S Durand, JC Portais… - Analytical …, 2010 - Elsevier
Functional metabolomics of skeletal muscle involves the simultaneous identification and
quantification of a large number of metabolites. For this purpose, the extraction of …

Serum metabolomic response of myasthenia gravis patients to chronic prednisone treatment

M Sengupta, A Cheema, HJ Kaminski, LL Kusner… - PLoS …, 2014 - journals.plos.org
Prednisone is often used for the treatment of autoimmune and inflammatory diseases but
they suffer from variable therapeutic responses and significant adverse effects. Serum …

The combination of four analytical methods to explore skeletal muscle metabolomics: Better coverage of metabolic pathways or a marketing argument?

C Bruno, F Patin, C Bocca, L Nadal-Desbarats… - … of Pharmaceutical and …, 2018 - Elsevier
Objectives Metabolomics is an emerging science based on diverse high throughput
methods that are rapidly evolving to improve metabolic coverage of biological fluids and …

Beyond the antibodies: serum metabolomic profiling of myasthenia gravis

D Blackmore, Z Siddiqi, L Li, N Wang, W Maksymowych - Metabolomics, 2019 - Springer
Introduction Myasthenia gravis (MG) is a chronic, potentially debilitating autoimmune
disease characterized by weakness and rapid fatigue of the voluntary muscles that worsens …

Biomarkers of skeletal muscle regulation, metabolism and dysfunction

J Shearer, AM Weljie - … and Systems Biology in Human Health …, 2014 - books.google.com
Skeletal muscle constitutes between 30 and 40% of typical body mass and is a major
metabolic engine in our daily lives (Janssen et al., 2000). Depending on body composition, it …