Understanding rotavirus vaccine efficacy and effectiveness in countries with high child mortality

T Varghese, G Kang, AD Steele - Vaccines, 2022 - mdpi.com
Rotavirus claims thousands of lives of children globally every year with a disproportionately
high burden in low-and lower-middle income countries where access to health care is …

Experiences with rotavirus vaccines: can we improve rotavirus vaccine impact in developing countries?

AD Steele, JC Victor, ME Carey, JE Tate… - Human vaccines & …, 2019 - Taylor & Francis
Rotavirus vaccines have been introduced into over 95 countries globally and demonstrate
substantial impact in reducing diarrheal mortality and diarrheal hospitalizations in young …

Rotavirus vaccines for infants in developing countries in Africa and Asia: considerations from a World Health Organization–sponsored consultation

AD Steele, M Patel, UD Parashar… - The Journal of …, 2009 - academic.oup.com
Abstract The World Health Organization (WHO) and its international partners have prioritized
the development of rotavirus vaccines for the past 3 decades. In November 2005, the WHO's …

Rotavirus vaccination and the global burden of rotavirus diarrhea among children younger than 5 years

C Troeger, IA Khalil, PC Rao, S Cao, BF Blacker… - JAMA …, 2018 - jamanetwork.com
Importance Rotavirus infection is the global leading cause of diarrhea-associated morbidity
and mortality among children younger than 5 years. Objectives To examine the extent of …

Options for improving effectiveness of rotavirus vaccines in developing countries

MS Tissera, D Cowley… - Human Vaccines & …, 2017 - Taylor & Francis
Rotavirus gastroenteritis is a leading global cause of mortality and morbidity in young
children due to diarrhea and dehydration. Over 85% of deaths occur in developing …

Rotavirus vaccines: effectiveness, safety, and future directions

E Burnett, U Parashar, J Tate - Pediatric Drugs, 2018 - Springer
Rotavirus is the leading cause of diarrheal death among children< 5 years old worldwide,
estimated to have caused~ 215,000 deaths in 2013. Prior to rotavirus vaccine …

Rotavirus vaccines: entering a new stage of deployment

O Nakagomi, NA Cunliffe - Current Opinion in Infectious Diseases, 2007 - journals.lww.com
Rotavirus vaccines are entering a new stage of deployment toward the goal of reducing
morbidity and mortality attributed to rotavirus infection in developing countries, and …

Differences of rotavirus vaccine effectiveness by country: likely causes and contributing factors

U Desselberger - Pathogens, 2017 - mdpi.com
Rotaviruses are a major cause of acute gastroenteritis in infants and young children
worldwide and in many other mammalian and avian host species. Since 2006, two live …

Rotavirus infections and vaccines: burden of illness and potential impact of vaccination

K Grimwood, SB Lambert, RJ Milne - Pediatric drugs, 2010 - Springer
Rotaviruses are the most common cause of severe gastroenteritis in children. By 5 years of
age virtually every child worldwide will have experienced at least one rotavirus infection …

Why does the world need another rotavirus vaccine?

RL Ward, MM McNeal, AD Steele - Therapeutics and Clinical Risk …, 2008 - Taylor & Francis
A “Meeting on Upstream Rotavirus Vaccines and Emerging Vaccine Producers” was held at
the World Health Organization in Geneva, Switzerland on March 28–30, 2006. The purpose …