Abstract The bridging integrator 1 (BIN1) gene is the second most important susceptibility
gene for late-onset Alzheimer's disease (LOAD) after apolipoprotein E (APOE) gene. To …

Genome-wide association studies have identified the bridging integrator 1 (BIN1) gene as
the most important genetic susceptibility locus in late-onset Alzheimer's disease (LOAD) …

Genome-wide association studies (GWAS) have identified a region upstream the BIN1 gene
as the most important genetic susceptibility locus in Alzheimer's disease (AD) after APOE …

Objective: The objective of this study was to evaluate the BIN1 3′ intergenic region DNA
methylation patterns in a Colombian sample of LOAD patients. Methods: A case-control …

BIN1, as an important genetic susceptibility locus in late-onset Alzheimer's disease (AD), is
overexpressed in AD brains. Our study investigated BIN1 diagnostic value by quantifying its …

Genome-wide association studies (GWAS) have identified several susceptibility loci of
Alzheimer's disease (AD), which were mainly located in noncoding regions of the genome …

Background: Bridging integrator 1 (BIN1) has been identified as one of the most associated
loci for Alzheimer's disease (AD), and recently was reported to modulate tau pathology to …

Alzheimer's disease (AD) is the most common form of dementia and exhibits a considerable
level of heritability. The bridging integrator 1 (BIN1) gene has recently been identified in …

Large-scale genome-wide association studies (GWAS) identified BIN1 gene rs744373
polymorphism to be significantly associated with Alzheimer's disease (AD) in Caucasian …

Bridging integrator 1 (BIN1) has been implicated in sporadic Alzheimer's disease (AD) by a
number of genome wide association studies (GWAS) in a variety of populations. Here we …