Amiodarone is commonly used for a variety of arrhythmias and, in some parts of the world, is
the only available antiarrhythmic drug (AAD). Yet, amiodarone is known to have a wide …

Objectives. We sought to assess the odds of experiencing adverse effects with low dose
amiodarone therapy compared with placebo. Background. An estimate of the likelihood of …

Methods Between January 1, 2000 and March 10, 2012, a total of 930 consecutive patients
who had been treated with amiodarone for arrhythmia were reviewed retrospectively. An …

Amiodarone has been associated with adverse events that may restrict its use. We
performed a meta-analysis of placebo-controlled trials to assess the relative risk of adverse …

Amiodarone is commonly used to treat supraventricular and ventricular arrhythmias in
various inpatient and outpatient settings. Over-and under-use of amiodarone is common …

ContextAlthough amiodarone is approved by the US Food and Drug Administration only for
refractory ventricular arrhythmias, it is one of the most frequently prescribed antiarrhythmic …

In this issue of the Journal, Vorperian et al.(1) present a statistically rigorous meta-analysis
of the adverse effects of low dose amiodarone (maintenance dose 400 mg/day) reported in …

The dataset presented here provides a detailed description of the adverse events of
amiodarone versus placebo using data from 43 randomized controlled trials. Two authors …

Cardiac arrhythmias are a cause of significant morbidity and mortality in patients with
cardiac disease, and thus represent a major management problem. The recognition that …

Introduction: Amiodarone is the most widely used antiarrhythmic agent, with demonstrated
effectiveness against all the spectrum of cardiac tachyarrhythmias. The risk of adverse …