Increased Nuclear FOXP2 Is Related to Reduced Neural Stem Cell Number and Increased Neurogenesis in the Dorsal Telencephalon of Embryos of Diabetic Rats …

DS De la Merced-García, Á Sánchez-Barrera… - Cells, 2023 - mdpi.com
Diabetic rat embryos have increased cortical neurogenesis and neuron maturation, and their
offspring presented altered neuron polarity, lamination, and diminished neuron excitability …

The histamine H1 receptor participates in the increased dorsal telencephalic neurogenesis in embryos from diabetic rats

KH Solís, LI Méndez, G García-López… - Frontiers in …, 2017 - frontiersin.org
Increased neuron telencephalic differentiation during deep cortical layer formation has been
reported in embryos from diabetic mice. Transitory histaminergic neurons within the …

Foxp2 regulates neuronal differentiation and neuronal subtype specification

YC Chiu, MY Li, YH Liu, JY Ding, JY Yu… - Developmental …, 2014 - Wiley Online Library
Mutations of the transcription factor FOXP2 in humans cause a severe speech and language
disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or …

[PDF][PDF] FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression

L Braccioli, SJ Vervoort, Y Adolfs, CJ Heijnen, O Basak… - Stem cell reports, 2017 - cell.com
Mutations in FOXP1 have been linked to neurodevelopmental disorders including
intellectual disability and autism; however, the underlying molecular mechanisms remain ill …

[HTML][HTML] FoxG1 directly represses dentate granule cell fate during forebrain development

X Han, X Gu, Q Zhang, Q Wang, Y Cheng… - Frontiers in Cellular …, 2018 - frontiersin.org
The cortex consists of 100s of neuronal subtypes that are organized into distinct functional
regions; however, the mechanisms underlying cell fate determination remain unclear. Foxg1 …

FOXG1 contributes adult hippocampal neurogenesis in mice

J Wang, HR Zhai, SF Ma, HZ Shi, WJ Zhang… - International Journal of …, 2022 - mdpi.com
Strategies to enhance hippocampal precursor cells efficiently differentiate into neurons
could be crucial for structural repair after neurodegenerative damage. FOXG1 has been …

Foxp1 Regulates Cortical Radial Migration and Neuronal Morphogenesis in Developing Cerebral Cortex

X Li, J Xiao, H Fröhlich, X Tu, L Li, Y Xu, H Cao, J Qu… - PloS one, 2015 - journals.plos.org
FOXP1 is a member of FOXP subfamily transcription factors. Mutations in FOXP1 gene have
been found in various development-related cognitive disorders. However, little is known …

Foxp1 suppresses cortical angiogenesis and attenuates HIF-1alpha signaling to promote neural progenitor cell maintenance

JE Buth, CE Dyevich, A Rubin, C Wang, L Gao… - EMBO …, 2024 - embopress.org
Neural progenitor cells within the cerebral cortex undergo a characteristic switch between
symmetric self-renewing cell divisions early in development and asymmetric neurogenic …

FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells

SHE Park, A Kulkarni, G Konopka - PLoS biology, 2023 - journals.plos.org
During cortical development, human basal radial glial cells (bRGCs) are highly capable of
sustained self-renewal and neurogenesis. Selective pressures on this cell type may have …

The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse

W Wang, L Su, F Ji, D Zhang, Y Wang, J Zhao… - EMBO …, 2022 - embopress.org
Cortical expansion and folding are key processes in human brain development and
evolution and are considered to be principal elements of intellectual ability. How cortical …