A major contributor to biomaterial associated infection (BAI) is Staphylococcus aureus. This
pathogen produces a protective biofilm, making eradication difficult. Biofilms are composed …

Bacterial biofilms causing implant-associated osteomyelitis is a severe complication with
limited antimicrobial therapy options. We designed an animal model, in which implant …

Bacterial biofilms in the body commonly occur following the implantation of a biomedical
device. A mature biofilm results in an extracellular matrix covering the aggregated bacteria …

Research indicates that the production of the nuclease enzyme in S. aureus cells has a
positive effect on rates of biofilm dispersal in vitro. In this document, we transform that …

Despite continuing progress in medical and surgical procedures, staphylococci remain the
major Gram-positive bacterial pathogens that cause a wide spectrum of diseases, especially …

Biofilms that form on implanted medical devices cause recalcitrant infections. The early
events enabling contaminating bacteria to evade immune clearance, before a mature biofilm …

The use of indwelling medical devices has constantly increased in recent years and has
revolutionized the quality of life of patients affected by different diseases. However, despite …

Staphylococcus aureus (S. aureus) biofilm is the major cause of failure of implant infection
treatment that results in heavy social and economic burden on individuals, families, and …

Staphylococcus aureus invasion of the osteocyte lacuno-canalicular network (OLCN) is a
novel mechanism of bacterial persistence and immune evasion in chronic osteomyelitis …