The formation of a biofilm on the implant surface is a major cause of intractable implant-
associated infection. To investigate the antibiotic concentration needed to eradicate the …

Implant associated infections represent a serious health burden in clinics since some
microorganisms are able to colonize biological surfaces or surfaces of indwelling medical …

While it is well known that Staphylococcus aureus establishes chronic implant‐associated
osteomyelitis by generating and persisting in biofilm, research to elucidate pathogen, and …

Implant infections in orthopaedics, as well as in many other medical fields, are chiefly
caused by staphylococci. The ability of growing within a biofilm enhances the chances of …

Introduction One of the main causes of treatment failure in bacterial prosthetic joint infections
(PJI) is biofilm formation. The topography of the biofilm may be associated with susceptibility …

Infection is a major complication of implantable medical devices, which provide a scaffold for
biofilm formation, thereby reducing susceptibility to antibiotics and complicating treatment …

Background Prosthetic implant infections caused by Staphylococcus aureus and
epidermidis are major challenges for early diagnosis and treatment owing to biofilm …

Background It has been well established that biofilm formation on orthopaedic implants is a
critical event in the pathogenesis of orthopaedic infections, yet the natural history of this …

Prosthesis and joint infections are an important threat in public health, especially due to the
development of bacterial biofilms and their high resistance to antimicrobials. Biofilm …

Orthopedic implant‐related bacterial infections are associated with high morbidity that may
lead to limb amputation and exert significant financial burden on the healthcare system …