New anti-tuberculosis drugs and regimens: 2015 update
L D'Ambrosio, R Centis, G Sotgiu, E Pontali… - ERJ Open …, 2015 - Eur Respiratory Soc
Over 480 000 cases of multidrug-resistant (MDR) tuberculosis (TB) occur every year
globally, 9% of them being affected by extensively drug-resistant (XDR) strains of …
globally, 9% of them being affected by extensively drug-resistant (XDR) strains of …
[PDF][PDF] Treatment of tuberculosis: present status and future prospects
P Onyebujoh, A Zumla, I Ribeiro… - Bulletin of the World …, 2005 - SciELO Public Health
Over recent years, tuberculosis (TB) and disease caused by human immunodeficiency virus
(HIV) have merged in a synergistic pandemic. The number of new cases of TB is stabilizing …
(HIV) have merged in a synergistic pandemic. The number of new cases of TB is stabilizing …
[HTML][HTML] Tuberculosis eradication versus control
Summary According to the World Health Organization (WHO), 10.4 million people died of
tuberculosis (TB) in 2015, and the disease is now the number one cause of death from a …
tuberculosis (TB) in 2015, and the disease is now the number one cause of death from a …
[HTML][HTML] Advancing the development of new tuberculosis treatment regimens: the essential role of translational and clinical pharmacology and microbiology
KE Dooley, D Hanna, V Mave, K Eisenach… - PLoS …, 2019 - journals.plos.org
Application of clinical pharmacology best practices is essential to the efficient and rational
development of drugs. In general, knowledge gained about exposure–response …
development of drugs. In general, knowledge gained about exposure–response …
Tuberculosis drug development: history and evolution of the mechanism-based paradigm
S Chakraborty, KY Rhee - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Modern tuberculosis (TB) chemotherapy is widely viewed as a crowning triumph of anti-
infectives research. However, only one new TB drug has entered clinical practice in the past …
infectives research. However, only one new TB drug has entered clinical practice in the past …
Recent advances in the treatment of tuberculosis
Background Tuberculosis (TB) is a global health challenge and one of the leading causes of
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
Tuberculosis drug development: progress, challenges, and the road ahead
AM Ginsberg - Tuberculosis, 2010 - Elsevier
Tuberculosis (TB) drug development has made substantial progress in the past decade.
There are currently at least ten drugs being evaluated in clinical trials. Some belong to …
There are currently at least ten drugs being evaluated in clinical trials. Some belong to …
[PDF][PDF] Technical report on the pharmacokinetics and pharmacodynamics (PK
World Health Organization - 2018 - apps.who.int
With an estimated 1.7 million deaths attributed to it each year, tuberculosis (TB) is the single
leading infectious cause of death in the world. Combined chemotherapy has been the …
leading infectious cause of death in the world. Combined chemotherapy has been the …
Tuberculosis pharmacotherapy: strategies to optimize patient care
CD Mitnick, B McGee, CA Peloquin - Expert opinion on …, 2009 - Taylor & Francis
Introduction: The treatment of tuberculosis (TB) is a mature discipline, with more than 60
years of clinical experience accrued across the globe. The requisite Multi-drug treatment of …
years of clinical experience accrued across the globe. The requisite Multi-drug treatment of …
Tuberculosis 2015: burden, challenges and strategy for control and elimination
M Raviglione, G Sulis - Infectious disease reports, 2016 - mdpi.com
Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide, accounting for
about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially …
about 9.6 million new cases and 1.5 million deaths annually. The poorest and socially …