[HTML][HTML] Comparing initial LABA-ICS inhalers in COPD: Real-world effectiveness and safety

S Suissa, S Dell'Aniello, P Ernst - Respiratory Medicine, 2021 - Elsevier
Background Guidelines for the treatment of chronic obstructive pulmonary disease (COPD)
patients with multiple exacerbations and eosinophilia recommend a long-acting beta 2 …

Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study

S Suissa, S Dell'Aniello, P Ernst - The Lancet Respiratory Medicine, 2018 - thelancet.com
Background Long-acting β 2 agonists (LABAs) and long-acting muscarinic antagonists
(LAMAs) are the recommended initial maintenance treatment for chronic obstructive …

Comparative effects of LAMA-LABA-ICS vs LAMA-LABA for COPD: cohort study in real-world clinical practice

S Suissa, S Dell'Aniello, P Ernst - Chest, 2020 - Elsevier
Background Triple therapy combinations of a long-acting muscarinic antagonist (LAMA), a
long-acting beta 2-agonist (LABA), and an inhaled corticosteroid (ICS) for COPD were …

Comparative effectiveness of budesonide/formoterol combination and fluticasone/salmeterol combination among chronic obstructive pulmonary disease patients new …

DM Kern, J Davis, SA Williams, O Tunceli, B Wu… - Respiratory …, 2015 - Springer
Background Inhaled corticosteroid/long-acting β 2-agonist combinations (ICS/LABA) have
emerged as first line therapies for chronic obstructive pulmonary disease (COPD) patients …

Comparative effectiveness and safety of LABA-LAMA vs LABA-ICS treatment of COPD in real-world clinical practice

S Suissa, S Dell'Aniello, P Ernst - Chest, 2019 - Elsevier
Background Long-acting β 2-agonists (LABAs) and long-acting muscarinic antagonists
(LAMAs) are recommended as initial maintenance treatments for COPD, with their …

Exacerbation outcomes with LAMA/LABA and ICS/LABA in high risk COPD patients in the IMPACT trial

DA Lipson, F Barnhart, I Boucot, C Crim, N Brealey… - 2018 - Eur Respiratory Soc
Rationale: Current GOLD strategy document positions both combination regimens of inhaled
corticosteroid plus a long-acting β 2-agonist [ICS/LABA] and LABA plus long-acting …

Overtreatment of COPD with inhaled corticosteroids-implications for safety and costs: cross-sectional observational study

P White, H Thornton, H Pinnock, S Georgopoulou… - PloS one, 2013 - journals.plos.org
Introduction Combined inhaled long-acting beta-agonists and corticosteroids (LABA+ ICS)
are costly. They are recommended in severe or very severe chronic obstructive pulmonary …

Comparing a fixed combination of budesonide/formoterol with other inhaled corticosteroid plus long-acting beta-agonist combinations in patients with chronic …

P Solidoro, F Patrucco, D Bagnasco - Expert Review of Respiratory …, 2019 - Taylor & Francis
Introduction: Inhaled corticosteroid (ICS) plus long-acting β2-agonist (LABA) combinations
are commonly used in the treatment of patients with chronic obstructive pulmonary disease …

Efficacy and safety of two doses of budesonide/formoterol fumarate metered dose inhaler in COPD

NA Hanania, A Papi, A Anzueto, FJ Martinez… - ERJ Open …, 2020 - Eur Respiratory Soc
Inhaled corticosteroid/long-acting β2-agonist combination therapy is a recommended
treatment option for patients with chronic obstructive pulmonary disease (COPD) and …

Evaluation of fluticasone propionate/salmeterol for the treatment of COPD: a systematic review

L Calzetta, BL Ritondo, MG Matera… - Expert Review of …, 2020 - Taylor & Francis
Introduction Recently, the generic formulation of FP/SAL FDC has been approved in COPD.
Although FP/SAL FDC has been the first long-acting FDC approved in COPD, no systematic …