Hereditary transthyretin amyloidosis (ATTRv) is a rare, progressive, and life-threatening
disease caused by misfolded transthyretin (TTR) proteins that aggregate as abnormal …

Transthyretin (ATTR) amyloidosis is a life-threatening, gain-of-toxic-function disease
characterised by extracellular deposition of amyloid fibrils composed of transthyretin (TTR) …

Hereditary transthyretin amyloidosis is caused by pathogenic variants (ATTR v) in the TTR
gene. Alongside cardiac dysfunction, the disease typically manifests with a severely …

Transthyretin familial amyloid polyneuropathy (TTR-FAP) is a fatal clinical disorder
characterized by extracellular deposition of abnormal fibrils derived from misfolded, normally …

Abstract Background: Hereditary transthyretin (ATTRm) amyloidosis is a rare, progressive
and fatal disease with a range of clinical manifestations. Objective: This study …

Familial amyloidosis (synonym for familiar amyloid polyneuropathy [FAP]) is an autosomal
dominant inherited disease, caused by mutations in the transthyretin (TTR) gene, coding for …

Abstract Transthyretin (TTR) amyloidosis (ATTR) is either an inherited condition or a non
hereditary disease due to misfolding of wild-type (WT) TTR. Amyloid deposits can be mainly …

Background Hereditary transthyretin (ATTRv, v for variant) amyloidosis with polyneuropathy
is a rare disease caused by mutations in the transthyretin gene. In ATTRv amyloidosis …

Transthyretin amyloidosis (ATTR) is a condition defined by accumulation of insoluble
transthyretin amyloid deposits in multiple organs, especially in the peripheral nerve and …

Systemic amyloidosis can be hereditary or acquired with autosomal dominant mutations in
the transthyretin gene (TTR) being the most common cause of hereditary amyloidosis …