Overview of bioactive fungal secondary metabolites: cytotoxic and antimicrobial compounds

R Conrado, TC Gomes, GSC Roque, AO De Souza - Antibiotics, 2022 - mdpi.com
Microorganisms are known as important sources of natural compounds that have been
studied and applied for different purposes in distinct areas. Specifically, in the …

Recent advances in search of bioactive secondary metabolites from fungi triggered by chemical epigenetic modifiers

M Xue, X Hou, J Fu, J Zhang, J Wang, Z Zhao, D Xu… - Journal of Fungi, 2023 - mdpi.com
Genomic analysis has demonstrated that many fungi possess essential gene clusters for the
production of previously unobserved secondary metabolites; however, these genes are …

Fungal secondary metabolites: ancient toxins and novel effectors in plant–microbe interactions

J Collemare, MH Lebrun - Effectors in plant–microbe …, 2011 - Wiley Online Library
Secondary metabolites (SMs) are low molecular weight compounds that are usually not
directly involved in growth (except siderophores) or in reproduction of their producing …

Structurally uncommon secondary metabolites derived from endophytic fungi

HE Ortega, D Torres-Mendoza, Z Caballero E… - Journal of Fungi, 2021 - mdpi.com
Among microorganisms, endophytic fungi are the least studied, but they have attracted
attention due to their high biological diversity and ability to produce novel and bioactive …

The past, present and future of secondary metabolite research in the D othideomycetes

MJ Muria‐Gonzalez, YH Chooi, S Breen… - Molecular plant …, 2015 - Wiley Online Library
The D othideomycetes represents a large and diverse array of fungi in which prominent
plant pathogens are over‐represented. Species within the C ochliobolus, A lternaria, P …

Multitrophic interactions of entomopathogenic fungi in BioControl

E Quesada-Moraga, I Garrido-Jurado… - BioControl, 2022 - Springer
Biocontrol with hypocrealean entomopathogenic fungi (EF) is a key tool to develop
Integrated Pest Management (IPM) programs for the progressive replacement of synthetic …

Secondary metabolite arsenal of an opportunistic pathogenic fungus

E Bignell, TC Cairns… - … of the Royal …, 2016 - royalsocietypublishing.org
Aspergillus fumigatus is a versatile fungus able to successfully exploit diverse environments
from mammalian lungs to agricultural waste products. Among its many fitness attributes are …

Diterpenes specially produced by fungi: Structures, biological activities, and biosynthesis (2010–2020)

FL Zhang, T Feng - Journal of Fungi, 2022 - mdpi.com
Fungi have traditionally been a very rewarding source of biologically active natural products,
while diterpenoids from fungi, such as the cyathane-type diterpenoids from Cyathus and …

Secondary metabolites from endophytic fungi: Production, methods of analysis, and diverse pharmaceutical potential

VK Singh, A Kumar - Symbiosis, 2023 - Springer
The synthesis of secondary metabolites is a constantly functioning metabolic pathway in all
living systems. Secondary metabolites can be broken down into numerous classes …

Fungal secondary metabolism: regulation, function and drug discovery

NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …