Background: A strategy for the treatment of type II diabetes mellitus is the inhibition of the
enzyme known as dipeptidyl peptidase-4 (DPP-4). Aims: This study aims to investigate the …

Dipeptidyl peptidase-4 (DPP-4) is an important biological target related to the treatment of
diabetes as DPP-4 inhibitors can lead to an increase in the insulin levels and a prolonged …

Dipeptidyl peptidase-4 (DPP-4) is the vital enzyme that is responsible for inactivating
intestinal peptides glucagon like peptide-1 (GLP-1) and Gastric inhibitory polypeptide (GIP) …

Literature data suggests that Dipeptidyl peptidase-4 (DPP-4) is a potential target for type 2
Diabetes Mellitus. Therefore, it is of interest to identify new DPP-4 inhibitors using molecular …

Diabetes is a metabolic disorder that presents hyperglycemia and vascular complications
due to the non-production of insulin or its inappropriate use by the body. One of the …

Dipeptidyl peptidase-4 (DPP-4) is considered a major drug target for type 2 diabetes mellitus
(T2DM). In addition to T2DM, a regulatory role of DPP-4 was also found in cardiovascular …

Dipeptidyl peptidase IV (DPP4) is an important target for the treatment of type II diabetes
mellitus. Inhibition of DPP4 will improve glycemic control in such patients by preventing the …

The development of potent, selective and orally bioactive Dipeptidyl Peptidase IV (DPP4)
inhibitors is the real challenge for the treatment of type II diabetes mellitus. Several DPP4 …

Diabetes mellitus (DM) is one of the largest public health problems worldwide and in the last
decades various therapeutic targetshave been investigated. For the treatment of type-2 DM …

Objectives: Type-2 diabetes mellitus, caused by impaired secretion of insulin, is becoming
one of the health hazardous threats to human lives across the world. Its prevalence is rising …