Aquaporin-4 (AQP4) is the main water channel protein expressed in the central nervous
system (CNS). AQP4 is densely expressed in astrocyte end-feet, and is an important factor in …

Aquaporin-4 (AQP4) is a predominant water channel protein in mammalian brains that is
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …

ABSTRACT Introduction: Aquaporin-4 (AQP4) is a water transporting protein expressed at
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …

Summary Aquaporin 4 (AQP 4) is the main water channel in the central nervous system
(CNS) and specifically localized to astrocyte processes. Recent studies indicate that AQP 4 …

Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

Of the several aquaporin (AQP) water channels expressed in the central nervous system,
AQP4 is an attractive target for drug discovery. AQP4 is expressed in astroglia, most strongly …

Aquaporin-4 (AQP4) is a water channel expressed on astrocytic endfeet in the brain. The
role of AQP4 has been studied in health and in a range of pathological conditions. Interest in …

The aquaporin (AQP) family of water channels are a group of small, membrane-spanning
proteins that are vital for the rapid transport of water across the plasma membrane. These …

Cerebrovascular diseases are conditions caused by problems with brain vasculature, which
have a high morbidity and mortality. Aquaporin-4 (AQP4) is the most abundant water …

Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the
central nervous system (CNS). AQP4 is widely expressed throughout the brain, especially at …