Overview of the Therapeutic Applications of Stem Cell–Derived Exosomes: A Research and Commercial Perspective

KA Heale, SC Nath, DE Rancourt - Current Protocols, 2021 - Wiley Online Library
Progress in extracellular vesicle (EV) research over the past two decades has generated
significant interest in using EVs in the biomedical field. Exosomes are a subgroup of EVs …

Frontier review of the molecular mechanisms and current approaches of stem cell-derived exosomes

LY Chen, TW Kao, CC Chen, N Niaz, HL Lee, YH Chen… - Cells, 2023 - mdpi.com
Exosomes are effective therapeutic vehicles that may transport their substances across cells.
They are shown to possess the capacity to affect cell proliferation, migration, anti-apoptosis …

[HTML][HTML] Stem Cell-Derived Exosomes as New Horizon for Cell-Free Therapeutic Development: Current Status and Prospects

D Vakil, R Doshi, F Mckinnirey… - … and Limitations in Current …, 2023 - intechopen.com
Exosomes have come a long way since they were first described in 1981 by Trams et al. as
small lipid bilayer-enclosed vesicles of endocytic origin. Their ability to alter cell bioactivity …

[HTML][HTML] Stem cell-based acellular therapy: insight into biogenesis, bioengineering and therapeutic applications of exosomes

MS Choudhery, T Arif, R Mahmood, DT Harris - Biomolecules, 2024 - pmc.ncbi.nlm.nih.gov
The vast regenerative potential of stem cells has laid the foundation for stem cell-based
therapies. However, certain challenges limit the application of cell-based therapies. The …

[HTML][HTML] Extracellular vesicles and their therapeutic applications: a review article (part 2)

D Rafieezadeh - International Journal of Physiology …, 2024 - pmc.ncbi.nlm.nih.gov
Extracellular vesicles (EVs) have emerged as a fascinating area of research in molecular
biology, with diverse therapeutic applications. These small membrane-bound structures …

Exosome-Based translational nanomedicine: The therapeutic potential for drug delivery

L Lv, Q Zeng, S Wu, H Xie, J Chen, XJ Guo… - Mesenchymal stem cell …, 2015 - Elsevier
Recent reports have shown that exosomes are specialized membranous nanosized vesicles
released by many cell types that have different biological effects and targeting specificities …

Stem Cell Based Exosomes: Are They Effective in Disease or Health?

MB Küçükgüven, B Çelebi-Saltik - … Medicine, Volume 13: Stem Cells in …, 2021 - Springer
Exosomes are nano-sized vesicles involved in intercellular communication via delivery of
molecules including lipids, nucleic acids, proteins, or other cellular components to distant or …

Stem cell-derived exosome versus stem cell therapy

K Zhang, K Cheng - Nature Reviews Bioengineering, 2023 - nature.com
Stem cell therapies are being explored for the treatment of various diseases, including
haematological disease, immune disease, neurodegenerative disease, and tissue injuries …

Techniques for increasing the yield of stem cell-derived exosomes: what factors may be involved?

ZY Feng, QY Zhang, J Tan, HQ Xie - Science China Life sciences, 2022 - Springer
Exosomes are nano-scale extracellular vesicles secreted by cells and constitute an
important part in the cell-cell communication. The main contents of the exosomes include …

[PDF][PDF] Mesenchymal stem cell-derived exosome: The likely game-changer in stem cell research

DKW Ocansey, X Xu, L Zhang, F Mao - Biocell, 2022 - academia.edu
Stem cell research is a promising area of transplantation and regenerative medicine with
tremendous potential for improving the clinical treatment and diagnostic options across a …