Real-world adherence for direct oral anticoagulants in a newly diagnosed atrial fibrillation cohort: does the dosing interval matter?

PN Pham, JD Brown - BMC Cardiovascular Disorders, 2019 - Springer
Background Differences in adherence may represent drug properties (eg dosing interval) or
patient experiences while on treatment. Adherence to direct oral anticoagulants (DOACs) in …

Patient adherence to novel oral anticoagulants (NOACs) for the treatment of atrial fibrillation and occurrence of associated bleeding events: a systematic review and …

A Shehab, AS Bhagavathula, TB Abebe… - Current vascular …, 2019 - ingentaconnect.com
Background: Real-world evidence from published observational studies of adherence to
Novel Oral Anticoagulants (NOACs) medications and associated clinical outcome events in …

Adherence and persistence to direct oral anticoagulants in atrial fibrillation: a population-based study

A Banerjee, V Benedetto, P Gichuru, J Burnell… - Heart, 2020 - heart.bmj.com
Background Despite simpler regimens than vitamin K antagonists (VKAs) for stroke
prevention in atrial fibrillation (AF), adherence (taking drugs as prescribed) and persistence …

Increased risk of stroke due to non-adherence and non-persistence with Direct Oral Anticoagulants (DOACs): real-world analyses using a nested case–control study …

E Holthuis, E Smits, G Spentzouris, D Beier… - Drugs-real world …, 2022 - Springer
Background A high degree of adherence to direct oral anticoagulants is essential for
reducing the risk of ischaemic stroke and systemic embolism in patients with atrial fibrillation …

Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation

A Charlton, X Vidal, M Sabaté, E Bailarín… - Journal of managed …, 2021 - jmcp.org
BACKGROUND: Direct oral anticoagulants (DOACs) are widely used for the prevention of
stroke in nonvalvular atrial fibrillation (NVAF); however, real-world primary nonadherence …

Modeling the impact of real-world adherence to once-daily (QD) versus twice-daily (BID) non-vitamin K antagonist oral anticoagulants on stroke and major bleeding …

CA McHorney, ED Peterson, V Ashton… - … medical research and …, 2019 - Taylor & Francis
Objectives: To estimate the real-world (RW) impact of adherence to once-daily (QD:
rivaroxaban and edoxaban) and twice-daily (BID: apixaban and dabigatran) non-vitamin K …

Prevalence and predictors of nonadherence to direct oral anticoagulant treatment in patients with atrial fibrillation

SFB van der Horst, TAC de Vries, G Chu, R Bavalia… - TH Open, 2023 - thieme-connect.com
Background For most patients with newly diagnosed atrial fibrillation (AF), direct oral
anticoagulants (DOACs) are preferred over vitamin K antagonists. However, there is concern …

A summary of the literature evaluating adherence and persistence with oral anticoagulants in atrial fibrillation

KO Obamiro, L Chalmers, LRE Bereznicki - American Journal of …, 2016 - Springer
Atrial fibrillation (AF) is a growing public health concern and remains an independent risk
factor for ischemic stroke. Warfarin, a commonly used oral anticoagulant, is associated with …

Primary nonadherence to oral anticoagulants in patients with atrial fibrillation: real-world data from a population-based cohort

CL Rodriguez-Bernal, S Peiró, I Hurtado… - Journal of managed …, 2018 - jmcp.org
BACKGROUND: Primary nonadherence (not filling a first prescription) is an important yet
unstudied aspect of adherence to oral anticoagulant (OAC) therapy. OBJECTIVE: To …

Long‐term medication adherence trajectories to direct oral anticoagulants and clinical outcomes in patients with atrial fibrillation

J An, Z Bider, TQ Luong, TC Cheetham… - Journal of the …, 2021 - Am Heart Assoc
Background Direct oral anticoagulants (DOACs) are widely used in patients with nonvalvular
atrial fibrillation for stroke prevention. However, long‐term adherence to DOACs and clinical …