Bubonic plague results when Yersinia pestis is deposited in the skin via the bite of an
infected flea. Bacteria then traffic to the draining lymph node (dLN) where they replicate to …

Yersinia pestis, the causative agent of plague, is typically transmitted by the bite of an
infected flea. Many aspects of mammalian innate immune response early after Y. pestis …

The majority of human Yersinia pestis infections result from introduction of bacteria into the
skin by the bite of an infected flea. Once in the dermis, Y. pestis can evade the host's innate …

ABSTRACT A hallmark of Yersinia pestis infection is a delayed inflammatory response early
in infection. In this study, we use an intradermal model of infection to study early innate …

Yersinia pestis causes bubonic plague, characterized by an enlarged, painful lymph node,
termed a bubo, that develops after bacterial dissemination from a fleabite site. In susceptible …

Yersinia pestis, the bacterial agent of plague, is transmitted to a mammalian host through the
bite of an infected flea. After deposition into the dermis, Y. pestis must subvert or prevent an …

Yersinia pestis is a gram-negative, zoonotic, bacterial pathogen, and the causative agent of
plague. The bubonic form of plague occurs subsequent to deposition of bacteria in the skin …

Vaccination with live attenuated Yersinia pestis confers protection against pneumonic
plague but is not considered safe for general use. Subunit plague vaccines containing the Y …

Yersinia pestis is the etiologic agent of plague that has killed more than 200 million people
throughout the recorded history of mankind. Antibiotics may provide little immediate relief to …

Neutrophils are the primary immune cell recruited to the site of bacterial infection, where
they can rapidly deploy vesicles filled with various pro-inflammatory and anti-microbial …