Context: Tachykinins (TKs), an evolutionarily conserved family of peptide hormones, are
widely distributed within the peripheral and central nervous systems. TKs exert their …

The possibility of links between phsychosocial factors and cancer incidence and
progression has generated considerable scientific and public interest. Tachykinins …

Tachykinins (TKs) and their receptors (NK1, NK2 and NK3), which are diffusely expressed in
the human gastrointestinal tract, represent an endogenous modulator system regulating …

Tachykinins (TKs) include an evolutionarily conserved group of small bio-active peptides
which possess a common carboxyl-terminal sequence, Phe-X-Gly-Leu-Met-NH2. TKs also …

In the gastrointestinal tract, tachykinins are peptide neurotransmitters in nerve circuits that
regulate intestinal motility, secretion, and vascular functions. Tachykinins also contribute to …

Background Tachykinins (TK s) are a family of endogenous peptides widely expressed in
the central and in the peripheral nervous systems as well as in the gastrointestinal (GI) tract …

Over 80 years has passed since the discovery of substance P (SP), and a variety of peptides
of the tachykinin (TK) family have been found and investigated. SP, neurokinin A (NKA), and …

Tachykinins (TKs) constitute the largest vertebrate brain/gut peptide family. Since discovery
of Substance P as a structurally unidentified vasodilatory and contractile compound in 1931 …

Tachykinins are a family of neuropeptides, involved in a variety of physiological and
pathological processes occurring in the gastrointestinal tract. They act via three distinct types …

Peptides of the tachykinin (TK) family were first discovered in the gastrointestinal tissue
about 75 years ago and supposed to be involved in gastrointestinal (GI) motility. This …