HLA DQ protein changes the cell surface distribution pattern of HLA proteins as monitored by Förster resonance energy transfer and high‐resolution electron …

J Kormos, AJ Veres, L Imre, L Mátyus, S Benkő… - Cytometry Part …, 2023 - Wiley Online Library
Peptide presentation by MHC class I and MHC class II molecules plays important roles in the
regulation of the immune response. One factor in these displays is the density of antigen …

Naturally processed peptides from HLA‐DQ7 (α1* 0501‐β1* 0301): influence of both α and β chain polymorphism in the HLA‐DQ peptide binding specificity

I Khalil‐Daher, F Boisgérault… - European journal of …, 1998 - Wiley Online Library
Self peptides bound to HLA‐DQ7 (α1* 0501‐β1* 0301), one of the HLA molecules
associated with protection against insulin‐dependent diabetes mellitus, were characterized …

HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule

C Lenormand, H Bausinger, F Gross… - The Journal of …, 2012 - journals.aai.org
The precise role of human epidermal Langerhans cells (LCs) in immune response is highly
controversial. While studying the gene expression profile of these cells, we were intrigued to …

Peptide presentation by HLA-DQ molecules is associated with the development of immune tolerance

M Manczinger, L Kemény - PeerJ, 2018 - peerj.com
HLA class II proteins are important elements of human adaptive immune recognition and are
associated with numerous infectious and immune-mediated diseases. These highly variable …

Allele-specific expression of the cytoplasmic exon of HLA-DQB1 gene

S Senju, A Kimura, M Yasunami, N Kamikawaji… - Immunogenetics, 1992 - Springer
The β chain of the HLA-DQ molecule is shorter by eight amino acid residues than other
major histocompatibility complex class II β chains due to elimination of the fifth exon coding …

Identification of an HLA‐DQ2 peptide binding motif and HLA‐DPw3‐bound self‐peptide by pool sequencing

FAW Verreck, A van de Poel… - European journal of …, 1994 - Wiley Online Library
Molecules of the major histocompatibility complex (MHC) present antigenic peptides to T
cells. Sequencing peptide pools eluted from MHC class I molecules has established allele …

Alloreactive T-cell clones identify multiple HLA-DQw3 variants

EM Mickelson, SA Masewicz, GT Nepom, PJ Martin… - Human immunology, 1991 - Elsevier
HLA-DQw3 is a broadly defined alloantigen that has been subdivided by serological,
biochemical, and molecular methods into three distinct specificities: DQw7, DQw8, and …

Divergent motifs but overlapping binding repertoires of six HLA-DQ molecules frequently expressed in the worldwide human population

J Sidney, A Steen, C Moore, S Ngo… - The Journal of …, 2010 - journals.aai.org
Abstract Knowledge of the binding repertoires and specificities of HLA-DQ molecules is
somewhat limited and contradictory, partly because of the scarcity of reports addressing …

Full-length DQβ cDNA sequences of HLA-DR2/DQw1 subtypes: Genetic interactions between two DQβ loci generate human class II HLA diversity

S Wu, D Lu, M Madden, CP Liu, N Miyokawa… - Human immunology, 1990 - Elsevier
Two-dimensional gel electrophoresis of DQ molecules from three different Dw subtypes
(Dw2, Dw12, and Dw21/FJO) of the HLA-DR2/DQw1 haplotype reveals that one αβ …

Both α and β chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with β chain residues being most influential

BH Johansen, T Jensen, CJ Thorpe, F Vartdal… - Immunogenetics, 1996 - Springer
We compared the peptide binding specificity of three HLA-DQ molecules; HLA-DQ (α1*
0501, β1* 0201), HLA-DQ (α1* 0201, β1* 0202), and HLA-DQ (α1* 0501, β1* 0301). The first …