Staphylococcus aureus and Streptococcus pyogenes (group A streptococci) are Gram‐
positive pathogens capable of producing a variety of bacterial exotoxins known as …

It has been 6 years since the novel concept of superantigen was proposed in 1989 in the
fields which cover immunology, microbiology and the study of infectious diseases (83) …

Superantigens are highly potent immune stimulators with a unique ability to interact
simultaneously with MHC class II molecules and T cell receptors, forming a trimolecular …

Superantigens (SAgs) include a class of certain bacterial and viral proteins exhibiting highly
potent lymphocyte-transforming (mitogenic) activity towards human and or other mammalian …

Normally, when a person's im mune system encounters a pro tein made by a virus or other
microbe, fewer than one in"'10,000 of the white blood cells known as T lym phocytes react …

Superantigens are a class of highly potent immuno-stimulatory molecules produced by
Staphylococcus aureus and Streptococcus pyogenes. These toxins possess the unique …

Staphylococcal superantigens (SEs and TSST-1) interact with and potentially activate two of
the main subsets of the immune system: T lymphocytes and MHC class II-positive cells …

The pyrogenic exotoxins of group A streptococci (SPEs) and the enterotoxins of
Staphylococcus aureus (SEs) constitute a family of structurally related toxins that also share …

Staphylococcal exotoxins, staphylococcal enterotoxins AE (SEA-SEE), and toxic shock
syndrome toxin-1 (TSST-1) are potent activators of the immune system and cause a variety …

Superantigens (SAgs) are a family of highly potent mitogens that share the ability to trigger
excessive stimulation of human and other mammalian T lymphocytes. This leads to a …