Food poisoning associated staphylococcal enterotoxins and other bacterial products of
diverse origin are now the focus of immunological research. These substances have special …

Superantigens (SAgs) are bacterial toxins that interact with immunoreceptors, T cell receptor
(TCR) and major histocompatibility complex (MHC) class II, conventionally through the …

Staphylococcal enterotoxin B (SEB) and related bacterial toxins cause diseases in humans
and laboratory animals ranging from food poisoning, acute lung injury to toxic shock. These …

The group A streptococcus produces a number of highly potent exoproteins that act as
superantigens. The cascade of pro-inflammatory events that follow invasive streptococcal …

Dimerization of MHC class II molecules on the cell surface of human THP-1 monocytic cell
line is a requirement for staphylococcal superantigen (SAG)-induced cytokine gene …

1. Jarraud S, Peyrat MA, Lim A, Tristan A, Bes M, Mougel C, Etienne J, Vandenesch F,
Bonneville M, Lina G. 2001. egc, a highly prevalent operon of enterotoxin gene, forms a …

Although it is well established that immune mechanisms contribute to the pathogenesis of
chronic inflammatory skin diseases such as atopic dermatitis (AD) and psoriasis, the actual …

Staphylococcal enterotoxin B (SEB) and related superantigenic toxins produced by
Staphylococcus aureus are potent activators of the immune system. These protein toxins …

▪ Abstract Superantigens (SAGs) are a class of immunostimulatory and disease-causing
proteins of bacterial or viral origin with the ability to activate large fractions (5–20%) of the T …

Bacterial products; including bacterial exotoxins, can ex-ert their immunomodulatory effects
on various lymphoid cell populations (6; ML Misfeldt, Clin. Microbiol. Newsl. 9: 21-24, 1988) …